Evidence map›Paper›PMID 36552753›Full record

ArticleCells2022

cfDNA Methylation Profiles and T-Cell Differentiation in Women with Endometrial Polyps.

Xiao-Hong Li, Mei-Yin Lu, Jia-Li Niu, Dong-Yan Zhu, Bin Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiao-Hong LiDepartment of Reproductive Health, Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen 518102, China.
Mei-Yin LuDepartment of Biobank, Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen 518102, China.
Jia-Li NiuDepartment of Biobank, Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen 518102, China.
Dong-Yan ZhuDepartment of Biobank, Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen 518102, China.
Bin LiuDepartment of Biobank, Shenzhen Baoan Women's and Children's Hospital, Jinan University, Shenzhen 518102, China.ORCID 0000-0001-5785-2579
Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation is a part of the regulatory mechanisms of gene expression, including chromatin remodeling and the activity of microRNAs, which are involved in the regulation of T-cell differentiation and function. However, the role of cfDNA methylation in T-cell differentiation is entirely unknown. In patients with endometrial polyps (EPs), we have found an imbalance of T-cell differentiation and an aberrant cfDNA methylation profile, respectively. In this study, we investigated the relationship between cfDNA methylation profiles and T-cell differentiation in 14 people with EPs and 27 healthy controls. We found that several differentially methylated genes (DMGs) were associated with T-cell differentiation in people with EPs (

Indexed as

Cell-Free Nucleic AcidsDNA MethylationPolypsT-LymphocytesUterine DiseasesCell DifferentiationFemaleHumansProtein Processing, Post-TranslationalCell-Free Nucleic AcidscfDNAendometrial polypetiologymethylationT-cell differentiation

Identifiers

PMID36552753
PMCPMC9777338
OpenAlexW4312125702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.