ReviewAntioxidants (Basel, Switzerland)2022
The Role of Lead and Cadmium in Gynecological Malignancies.
Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Environmental and public health outcomes following the Fundão dam collapse (Mariana, Brazil): a retrospective ecological study of drinking water quality and cancer mortality.Lancet regional health. Americas · 2026Article
- Systematic Review and Meta-Analysis on the Association Between Cadmium and Mercury, with Polycystic Ovary Syndrome.Biological trace element research · 2026Review
- Article
- The Association Between Cadmium Exposure and Endometrial Cancer Risk: Evidence from a Comprehensive Updated Meta-Analysis.Journal of clinical medicine · 2026Review
- Article
- Post-pubertal Susceptibility to Cadmium-Induced Cardiac Injury: Role of Metallothionein, Antioxidant Defense, and Endocrine Modulation.Cardiovascular toxicology · 2025Article
- Baseline exposure-response assessment of metals from dried blood spots and personal household air pollution concentrations among pregnant women in Rwanda: household air pollution intervention network trial.Journal of health, population, and nutrition · 2025Article
- Article
- Review
- The Role of Heavy Metals in the Biology of Female Cancers.International journal of molecular sciences · 2025Review
- Evaluation of Health Risks Associated with Potential Toxic Elements in Selected Vegetables Consumed in the Western Black Sea Region of Turkey.ACS omega · 2025Article
- Categorizing high-grade serous ovarian carcinoma into clinically relevant subgroups using deep learning-based histomic clusters.Journal of pathology and translational medicine · 2025Article
- The Combined Effects of Urine Zinc, Cadmium, Mercury, Lead, and Copper on Endometrial Cancer Staging.International journal of environmental research and public health · 2025Article
- Blood lead levels and bladder cancer among US participants: NHANES 1999-2018.BMC public health · 2025Article
- Association between heavy metal exposure and bacterial vaginosis: A cross-sectional study.PloS one · 2025Article
- Qualitative and quantitative water investigation of Erin-Ijesha (Olumirin) Waterfall, Erin-Ijesha, Nigeria.Heliyon · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lead and cadmium are non-essential and toxic heavy metals. Their presence and elevated levels can lead to many pathologies. They disrupt the antioxidant properties of many enzymes, consume the resources of antioxidant cells, and thus participate in the generation of oxidative stress, which may result in DNA damage. In addition, they have been found to be carcinogenic through their genotoxic properties. They have been shown to be present in various types of cancer, including cancer of the female reproductive system. Both metals have been recognized as metalloestrogens, which are important in hormone-related cancers. Participation in the oncogenesis of ovarian, endometrial and cervical cancer was analysed in detail, using the available research in this field. We emphasize their role as potential biomarkers in cancer risk and diagnosis as well as advancement of gynaecological malignancies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.