Evidence map›Paper›PMID 36552547›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Antioxidant and Hepatoprotective Effect of a Nutritional Supplement with Silymarin Phytosome, Choline Chloride, l-Cystine, Artichoke, and Vitamin E in Dogs.

Claudia Giannetto, Francesca Arfuso, Elisabetta Giudice, Maria Rizzo, Giuseppe Piccione, Kamel Mhalhel, Maria Levanti

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Effects ofVeterinary sciences · 2025
    Article
  6. Oxidative Stress in Canine Diseases: A Comprehensive Review.Antioxidants (Basel, Switzerland) · 2024
    Review
  7. Review
  8. Supplementation withAnimals : an open access journal from MDPI · 2024
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Claudia GiannettoDepartment of Veterinary Sciences, Polo Universitario dell'Annunziata, University of Messina, 98168 Messina, Italy.ORCID 0000-0003-3049-1181
Francesca ArfusoDepartment of Veterinary Sciences, Polo Universitario dell'Annunziata, University of Messina, 98168 Messina, Italy.ORCID 0000-0001-6139-2691
Elisabetta GiudiceDepartment of Veterinary Sciences, Polo Universitario dell'Annunziata, University of Messina, 98168 Messina, Italy.
Maria RizzoDepartment of Veterinary Sciences, Polo Universitario dell'Annunziata, University of Messina, 98168 Messina, Italy.ORCID 0000-0003-4343-8937
Giuseppe PiccioneDepartment of Veterinary Sciences, Polo Universitario dell'Annunziata, University of Messina, 98168 Messina, Italy.ORCID 0000-0002-4736-1087
Kamel MhalhelDepartment of Veterinary Sciences, Polo Universitario dell'Annunziata, University of Messina, 98168 Messina, Italy.ORCID 0000-0002-9432-4588
Maria LevantiDepartment of Veterinary Sciences, Polo Universitario dell'Annunziata, University of Messina, 98168 Messina, Italy.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phytotherapy has been promoted for the treatment of liver diseases in dogs. The interest in identifying the antioxidant/hepatoprotective potential of various plants is increasing. Every 10 days for 30 days, forty dogs were subjected to blood sampling and hepatic ultrasound assessment. Clinically healthy dogs (group A) and dogs with liver enzyme and ultrasound hepatic aspects and sizes outside the physiological range (group B) were divided into two subgroups. Every day for 30 days, one subgroup received Epacare pet + pasta

Indexed as

antioxidantsdogsfood supplementhepatoprotectionsilymarin phytosome

Identifiers

PMID36552547
PMCPMC9774582
OpenAlexW4310211439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.