Evidence map›Paper›PMID 36552521›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Recombinant Photolyase-Thymine Alleviated UVB-Induced Photodamage in Mice by Repairing CPD Photoproducts and Ameliorating Oxidative Stress.

Zhaoyang Wang, Ziyi Li, Yaling Lei, Yuan Liu, Yuqing Feng, Derong Chen, Siying Ma, Ziyan Xiao, Meirong Hu, Jingxian Deng and 4 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Zhaoyang WangDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Ziyi LiTYRAN Cosmetics Innovation Research Institute, Jinan University, Guangzhou 511447, China.
Yaling LeiDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Yuan LiuDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Yuqing FengDepartment of Pharmacology, Jinan University, Guangzhou 510632, China.
Derong ChenDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Siying MaDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Ziyan XiaoDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Meirong HuDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Jingxian DengDepartment of Pharmacology, Jinan University, Guangzhou 510632, China.
Yuxin WangDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Qihao ZhangDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Yadong HuangDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.
Yan YangDepartment of Cell Biology, Jinan University, Guangzhou 510632, China.ORCID 0000-0001-7835-4309
Jinan University · CN

Funding

National Natural Science Foundation of China 32170865National Natural Science Foundation of China 81871150National Natural Science Foundation of China 82071634Natural Science Foundation of Guangdong Province 2022A1515012178
6 · The paper itself

Abstract

Cyclobutane pyrimidine dimers (CPDs) are the main mutagenic DNA photoproducts caused by ultraviolet B (UVB) radiation and represent the major cause of photoaging and skin carcinogenesis. CPD photolyase can efficiently and rapidly repair CPD products. Therefore, they are candidates for the prevention of photodamage. However, these photolyases are not present in placental mammals. In this study, we produced a recombinant photolyase-thymine (rPHO) from

Indexed as

DNA damageoxidative stressphotorepairrecombinant photolyase

Identifiers

PMID36552521
PMCPMC9774824
OpenAlexW4309721137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.