Evidence map›Paper›PMID 36552440›Full record

ArticleAnimals : an open access journal from MDPI2022

Growth-Promoting Effects of Zhenqi Granules on Finishing Pigs.

Wentao Luo, Yaxue Huang, Xiuxiu Qiu, Wenxiao Zhuo, Yujun Tao, Shuaiyang Wang, Huaixia Li, Jing Shen, Lelin Zhao, Lijun Zhang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Wentao LuoState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.ORCID 0000-0002-7630-1753
Yaxue HuangState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Xiuxiu QiuState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Wenxiao ZhuoState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Yujun TaoState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Shuaiyang WangState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Huaixia LiState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Jing ShenState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Lelin ZhaoState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Lijun ZhangState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Shuo LiHubei Provincial Veterinary Drug Research Center, HVSEN Biotech, Wuhan 430042, China.
Jie LiuHubei Provincial Veterinary Drug Research Center, HVSEN Biotech, Wuhan 430042, China.
Qi HuangState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.
Rui ZhouState Key Laboratory of Agricultural Microbiology, and Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University College of Veterinary Medicine, Wuhan 430070, China.ORCID 0000-0002-7903-9965
Huazhong Agricultural University · CN

Funding

National Key Research and Development Plans 2018YFE0101600
6 · The paper itself

Abstract

Developing nonantibiotic livestock growth promoters attracts intensive interest in the post-antibiotic era. In this study, we investigated the growth-promoting efficacy of Zhenqi granules (ZQ) in pigs and further explored the possible mechanisms by transcriptomics analysis. Weaned piglets (52 days old with an average body weight of 17.92 kg) were fed with diets supplemented with different doses of ZQ (0 g/kg, 1 g/kg, and 2 g/kg) for 30 days and continued observations for an additional 32 days after removing ZQ from the diets. Compared with the control group, the average daily gain, carcass weight, average back fat thickness, and fat meat percentage of the group supplemented with 1 g/kg of ZQ showed a significant increase, and the feed/gain ratio was lower. The group supplemented with 2 g/kg of ZQ also showed a significant increase in average daily gain and average backfat thickness. A transcriptomics analysis revealed that the supplementation of ZQ at 1 g/kg upregulated the expression of genes related to collagen biosynthesis and lipid biosynthesis in skeletal muscle and liver. This effect was primarily through upregulating the mRNA levels of structural proteins and lipid-related enzymes. This study demonstrates the growth-promoting efficacy of ZQ and provides some insights of the mechanism of growth promotion.

Indexed as

carcass traitsfinishing pigsgrowth promotiontranscriptomicsZhenqi granules

Identifiers

PMID36552440
PMCPMC9774107
OpenAlexW4311392178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.