Evidence map›Paper›PMID 36552027›Full record

ArticleBiomedicines2022

Differential Regulation of MMPs, Apoptosis and Cell Proliferation by the Cannabinoid Receptors CB1 and CB2 in Vascular Smooth Muscle Cells and Cardiac Myocytes.

Bettina Greiner, Manuela Sommerfeld, Ulrich Kintscher, Thomas Unger, Kai Kappert, Elena Kaschina

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Impact of Marijuana (Iranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bettina GreinerCardiovascular-Metabolic-Renal (CMR)-Research Center, Institute of Pharmacology, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany.
Manuela SommerfeldCardiovascular-Metabolic-Renal (CMR)-Research Center, Institute of Pharmacology, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany.
Ulrich KintscherCardiovascular-Metabolic-Renal (CMR)-Research Center, Institute of Pharmacology, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany.
Thomas UngerCARIM School for Cardiovascular Diseases, Maastricht University, 6211 LK Maastricht, The Netherlands.
Kai KappertDZHK (German Centre for Cardiovascular Research), partner site Berlin, 10115 Berlin, Germany.ORCID 0000-0001-6976-0428
Elena KaschinaCardiovascular-Metabolic-Renal (CMR)-Research Center, Institute of Pharmacology, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany.
Humboldt-Universität zu Berlin · DEMaastricht University · NL

Funding

Deutsche Forschungsgemeinschaft KI 712/10-1, KA 1820/9-1, KA 1820/10-1DZHK BER 5.4 PREinstein Foundation/Foundation Charité EVF-BIH-2018-440
6 · The paper itself

Abstract

Cannabinoids (CB) are implicated in cardiovascular diseases via the two main receptor subtypes CB

Indexed as

apoptosiscannabinoid receptorscardiovascular diseasecell proliferationglucoseH9c2 cellsMMP-2MMP-9VSMC

Identifiers

PMID36552027
PMCPMC9775096
OpenAlexW4312141190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.