Evidence map›Paper›PMID 36551898›Full record

ReviewBiomedicines2022

Secondary Terpenes in

Francisco T Chacon, Wesley M Raup-Konsavage, Kent E Vrana, Joshua J Kellogg

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Comparative Anti-Obesity Potential of Cannabigerol-DominantInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Haploid Production inBiology · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Impact of Soil Quality on Cannabinoid and Terpenoid Content ofJournal of medicinally active plants · 2025
    Article
  16. Article
  17. Article
  18. Antimicrobial, Probiotic, and Immunomodulatory Potential ofAntibiotics (Basel, Switzerland) · 2024
    Article
  19. The Neurotherapeutic Arsenal inMolecules (Basel, Switzerland) · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Francisco T ChaconIntercollege Graduate Degree Program in Plant Biology, Pennsylvania State University, University Park, State College, PA 16802, USA.ORCID 0000-0002-0199-6810
Wesley M Raup-KonsavageDepartment of Pharmacology, Penn State College of Medicine, Hershey, PA 17033, USA.ORCID 0000-0001-9413-9852
Kent E VranaDepartment of Pharmacology, Penn State College of Medicine, Hershey, PA 17033, USA.
Joshua J KelloggIntercollege Graduate Degree Program in Plant Biology, Pennsylvania State University, University Park, State College, PA 16802, USA.ORCID 0000-0001-8685-0353
Pennsylvania State University · US

Funding

PA Options for Wellness Penn State College of MedicineUSDA National Institute of Food and Agriculture Hatch Appropriations PEN04772
6 · The paper itself

Abstract

Cannabis is a complex biosynthetic plant, with a long history of medicinal use. While cannabinoids have received the majority of the attention for their psychoactive and pharmacological activities, cannabis produces a diverse array of phytochemicals, such as terpenes. These compounds are known to play a role in the aroma and flavor of cannabis but are potent biologically active molecules that exert effects on infectious as well as chronic diseases. Furthermore, terpenes have the potential to play important roles, such as synergistic and/or entourage compounds that modulate the activity of the cannabinoids. This review highlights the diversity and bioactivities of terpenes in cannabis, especially minor or secondary terpenes that are less concentrated in cannabis on a by-mass basis. We also explore the question of the entourage effect in cannabis, which studies to date have supported or refuted the concept of synergy in cannabis, and where synergy experimentation is headed, to better understand the interplay between phytochemicals within

Indexed as

biosynthesiscannabinoidscannabisentourage effectphytochemistrysynergyterpenes

Identifiers

PMID36551898
PMCPMC9775512
OpenAlexW4311724840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.