Evidence map›Paper›PMID 36551896›Full record

ArticleBiomedicines2022

Methylenetetrahydrofolate Reductase C677T Gene Variant in Relation to Body Mass Index and Folate Concentration in a Polish Population.

Małgorzata Wrzosek, Klaudia Ślusarczyk

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. International journal of molecular medicine · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Małgorzata WrzosekDepartment of Biochemistry and Pharmacogenomics, Medical University of Warsaw, 1 Banacha St., 02-097 Warsaw, Poland.ORCID 0000-0002-9820-3871
Klaudia ŚlusarczykDepartment of Biochemistry and Pharmacogenomics, Medical University of Warsaw, 1 Banacha St., 02-097 Warsaw, Poland.
Medical University of Warsaw · PL

Funding

Medical University of Warsaw Medical University of Warsaw under Grants FW113/NM1/17, FW113/PM2/17, 14/F/MG/21Ministry of Education and Science Ministry of Education and Science in Poland (SKN/SP/496250/2021)
6 · The paper itself

Abstract

backgroundMethylenetetrahydrofolate reductase (MTHFR) is an enzyme responsible for producing an active form of folate. The

aimIn this study, we examined the influence of the

methodsThe study group consisted of 1712 Caucasian adults of Polish nationality with a wide range of body mass indexes (BMIs). DNA was extracted from the blood, and the C677T variant was tested with RFLP-PCR and real-time-PCR.

resultsThere was no significant influence found for the

conclusionAlthough the

Indexed as

BMIfolatemethylenetetrahydrofolate reductaseMTHFR C677T

Identifiers

PMID36551896
PMCPMC9775363
OpenAlexW4311636705

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.