ReviewBiomedicines2022
How to Manage a Patient with Ocular Metastases?
Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Clinical manifestation and outcome of lung cancer patients with ocular metastasis: 16 case reports and systematic review.Thoracic cancer · 2024Pooled it
- Intraocular Metastasis: Differential Diagnosis and Management.Clinical & experimental ophthalmology · 2026Review
- A Case of a Metastatic Tumor to the Extraocular Muscles from Endometrial Carcinoma.NMC case report journal · 2026Article
- Dramatic Inflammatory Regression of Choroidal Metastases from Renal Cell Carcinoma following Ipilimumab and Nivolumab Immunotherapy: A Case Series.Ocular oncology and pathology · 2025Article
- Brachytherapy for choroidal metastasis secondary to primary urethral adenocarcinoma of Müllerian origin: A case report.American journal of ophthalmology case reports · 2025Article
- Radiation-induced maculopathy and fluocinolone acetonide implant.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Observational
- Choroidal metastasis as the first sign of small cell lung cancer: A case report.Oncology letters · 2025Article
- Article
- Review
- Ocular metastasis in breast cancer: management of clinical case reports and a literature review.Frontiers in oncology · 2025Article
- Choroidal metastases from thoracic cancer: a retrospective study on clinical characteristics and treatment efficacy.Frontiers in medicine · 2025Article
- Article
- Right eye metastasis of small‑cell lung carcinoma: A case report.Experimental and therapeutic medicine · 2024Article
- [Staging and systemic treatment of ocular and periocular metastases].Die Ophthalmologie · 2024Review
- [Clinical approach for solid intraocular metastases].Die Ophthalmologie · 2024Review
- Rapid progress of an iris metastasis from esophageal cancer: a case report and review of literature.International journal of ophthalmology · 2024Review
- Intensity-Modulated Radiation Therapy for Bilateral Choroidal Metastases Involving Macula and Optic Disc.Cureus · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ocular metastases are the most frequent ocular malignant tumors; their prevalence is estimated around 5-10% and is even higher in patients with breast or lung cancer. They represent various clinical situations, but they share the same hierarchical multidisciplinary therapeutic challenge with respect to the way systemic and local therapies should be selected in combination or sequentially in the personalized medical history of a patient. The challenges include tumor control, eye preservation, and the minimization of iatrogenic damage to sensitive tissues surrounding the tumor in order to preserve vision. These aims should further contribute to maintaining quality of life in patients with metastases. Many patients with choroidal metastases have systemic molecular treatment for their primary tumor. However, secondary resistance to systemic treatment is common and may ultimately be associated with cancer relapse, even after an initial response. Therefore, it makes sense to propose local treatment concomitantly or after systemic therapy to provide a more sustainable response. The aim of this review is to present current therapeutic strategies in ocular metastases and discuss how to tailor the treatment to a specific patient.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.