ReviewCancers2022
Current Knowledge on Spinal Meningiomas-Surgical Treatment, Complications, and Outcomes: A Systematic Review and Meta-Analysis (Part 2).
Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Rates of recurrence and symptom improvement following resection of spinal meningiomas in the pediatric population: individual participant data meta-analysis.Journal of neuro-oncology · 2026Pooled it
- Resection vs. coagulation of dural attachment in patients with spinal meningioma: an updated systematic review and meta-analysis.Acta neurochirurgica · 2024Pooled it
- The use of hybrid operating rooms in neurosurgery, advantages, disadvantages, and future perspectives: a systematic review.Acta neurochirurgica · 2023Pooled it
- Urinary dysfunction in spinal meningiomas: a significant disease severity marker in a cohort of 165 patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Contralateral vs. ipsilateral hemilaminectomy for spinal meningiomas: impact on resection completeness, stability, and recurrence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Giant Thoracic Meningioma: Missed Diagnosis and Challenging Management in a Resource-Limited Setting.Cureus · 2026Article
- Extracellular vesicle-based therapeutic strategies for spinal tumors and associated nerve damage: advances, challenges, and future directions.Frontiers in cell and developmental biology · 2026Review
- Evaluation of magnetic resonance imaging and deep learning-based synthetic computed tomography for calcified intradural tumors - importance of domain-specific training and validation of synthetic imaging methods for clinical application.Acta neurochirurgica · 2025Observational
- High-frequency ultrasonic osteotomy in the treatment of intradural spinal tumors: matched cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Tumour distribution and characteristics associated with poor surgical outcomes in patients with sporadic spinal schwannomas.Acta neurochirurgica · 2025Article
- Epidemiology, tumour characteristics, treatment and outcomes associated with spinal nerve sheath tumours: a systematic review protocol.BMJ open · 2024Article
- Clinical, molecular, and genetic features of spinal meningiomas.Neuro-oncology advances · 2024Review
- Timing of Resection of Spinal Meningiomas and Its Influence on Quality of Life and Treatment.Cancers · 2024Article
- Optical Methods for Brain Tumor Detection: A Systematic Review.Journal of clinical medicine · 2024Review
- Review
- One-piece resection for the treatment of ventral intradural extramedullary spinal meningioma: a retrospective study.Frontiers in oncology · 2024Article
- Article
- High grade spinal meningiomas: a rare but formidable challenge.Translational cancer research · 2023Article
- Spontaneous spinal cord infarctions: a systematic review and pooled analysis protocol.BMJ open · 2023Article
- Clinical features and surgical outcomes of primary spinal anaplastic meningioma: a cases series and literature review.Translational cancer research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Most of the knowledge on spinal meningiomas is extrapolated from their intracranial counterparts, even though they are considered separate entities. This review aimed to systematically summarize studies covering different aspects of spinal meningiomas and their management. Methods: Databases were searched for all studies concerning spinal meningiomas dating from 2000 and onwards. When possible, a meta-analysis was performed. Results: Neurological outcomes of surgery were consistently favorable across studies, with a complication rate of 7.9% and 78.9% of the patients demonstrating good postoperative neurological function (McCormick score 1−2). The most relevant predictors of unfavorable outcomes were poor preoperative status, longer time from diagnosis to surgery, and surgery of recurrent tumors. The recurrence rate after surgery was estimated at 6%. Meta-analysis and/or survival analysis revealed that higher WHO grade (p < 0.001), higher Simpson grade (p < 0.001), ventral tumor location (p = 0.02), and male sex (p = 0.014) were all associated with higher odds of recurrence. However, the meta-analysis did not show any difference between Simpson grade 1 and grade 2 with respect to the odds of recurrence (p = 0.94). Surgery provided immediate and durable health-related quality-of-life improvement, as well as a high frequency of return to work. Conclusion: Spinal meningioma surgery is a relatively safe procedure with a low risk of tumor recurrence and high likelihood of favorable postoperative outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.