Evidence map›Paper›PMID 36551606›Full record

ReviewCancers2022

The Role of Radiomics and AI Technologies in the Segmentation, Detection, and Management of Hepatocellular Carcinoma.

Dalia Fahmy, Ahmed Alksas, Ahmed Elnakib, Ali Mahmoud, Heba Kandil, Ashraf Khalil, Mohammed Ghazal, Eric van Bogaert, Sohail Contractor, Ayman El-Baz

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Estimation of tumor coverage after RF ablation of hepatocellular carcinoma using single 2D image slices.International journal of computer assisted radiology and surgery · 2025
    Trial
  3. Suppression of NGALR impedes TNBC cell survival, proliferation, invasion, and migration through Akt/mTOR and JAK/STAT3 pathway inhibition.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. [New progress in the technology of non-invasive diagnosis for small hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Dalia FahmyDiagnostic Radiology Department, Mansoura University Hospital, Mansoura 35516, Egypt.ORCID 0000-0002-8221-4226
Ahmed AlksasBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0001-9409-931X
Ahmed ElnakibBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0001-6084-3622
Ali MahmoudBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0003-2557-9699
Heba KandilBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0002-5531-5574
Ashraf KhalilCollege of Technological Innovation, Zayed University, Abu Dhabi 4783, United Arab Emirates.ORCID 0000-0003-1584-8525
Mohammed GhazalElectrical, Computer, and Biomedical Engineering Department, Abu Dhabi University, Abu Dhabi 59911, United Arab Emirates.ORCID 0000-0002-9045-6698
Eric van BogaertDepartment of Radiology, University of Louisville, Louisville, KY 40202, USA.
Sohail ContractorDepartment of Radiology, University of Louisville, Louisville, KY 40202, USA.
Ayman El-BazBioengineering Department, University of Louisville, Louisville, KY 40292, USA.ORCID 0000-0001-7264-1323
University of Louisville · USAbu Dhabi University · AEMansoura University Hospital · EGZayed University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the most common primary hepatic neoplasm. Thanks to recent advances in computed tomography (CT) and magnetic resonance imaging (MRI), there is potential to improve detection, segmentation, discrimination from HCC mimics, and monitoring of therapeutic response. Radiomics, artificial intelligence (AI), and derived tools have already been applied in other areas of diagnostic imaging with promising results. In this review, we briefly discuss the current clinical applications of radiomics and AI in the detection, segmentation, and management of HCC. Moreover, we investigate their potential to reach a more accurate diagnosis of HCC and to guide proper treatment planning.

Indexed as

AIcomputed tomographydeep learninghepatocellular carcinomamachine learning

Identifiers

PMID36551606
PMCPMC9777232
OpenAlexW4311350453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.