Evidence map›Paper›PMID 36551560›Full record

ArticleCancers2022

Evolution of

Manuel Valladares-Ayerbes, Pilar Garcia-Alfonso, Jorge Muñoz Luengo, Paola Patricia Pimentel Caceres, Oscar Alfredo Castillo Trujillo, Rosario Vidal-Tocino, Marta Llanos, Beatriz Llorente Ayala, Maria Luisa Limon Miron, Antonieta Salud and 13 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Association of ctDNAJournal of gastrointestinal oncology · 2026
    Article
  2. Review
  3. Review
  4. Sequential RAS mutations evaluation in cell-free DNA of patients with tissue RAS wild-type metastatic colorectal cancer: the PERSEIDA (Cohort 2) study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Observational
  5. Article
  6. Evaluation ofCells · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Manuel Valladares-AyerbesHospital Universitario Virgen del Rocío, 41013 Sevilla, Spain.
Pilar Garcia-AlfonsoHospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-4373-9978
Jorge Muñoz LuengoHospital San Pedro de Alcántara, 10003 Cáceres, Spain.
Paola Patricia Pimentel CaceresComplejo Hospitalario Area II de Cartagena, Hospital Universitario Santa Lucia, 30202 Cartagena, Spain.
Oscar Alfredo Castillo TrujilloHospital Universitario Central de Asturias, ISPA, 33011 Oviedo, Spain.ORCID 0000-0001-7479-8658
Rosario Vidal-TocinoComplejo Asistencial Universitario de Salamanca, IBSAL, 37007 Salamanca, Spain.ORCID 0000-0002-0588-2001
Marta LlanosHospital Universitario de Canarias, 38320 San Cristóbal de La Laguna, Spain.
Beatriz Llorente AyalaHospital Universitario de Burgos, 09006 Burgos, Spain.
Maria Luisa Limon MironHospital Universitario Virgen del Rocío, 41013 Sevilla, Spain.
Antonieta SaludHospital Universitario Arnau de Vilanova, 25198 Lleida, Spain.
Luis Cirera NoguerasHospital Mutua de Terrassa, 08221 Terrassa, Spain.
Rocio Garcia-CarboneroHospital Universitario 12 de Octubre, Imas12, UCM, 28041 Madrid, Spain.
Maria Jose SafontHospital General Universitario de Valencia, 46014 València, Spain.ORCID 0000-0003-4584-0452
Esther Falco FerrerHospital Universitari Son Llàtzer, 07198 Palma, Spain.
Jorge AparicioHospital Universitari i Politècnic La Fe, 46026 València, Spain.
Maria Angeles Vicente ConesaHospital General Universitario José Maria Morales Meseguer, 30008 Murcia, Spain.
Carmen Guillén-PonceHospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0002-3594-1084
Paula Garcia-TeijidoHospital Universitario San Agustín, 33401 Avilés, Spain.
Maria Begoña Medina MaganHospital Universitario Torrecárdenas, 04009 Almería, Spain.
Isabel BusquierConsorcio Hospitalario Provincial de Castellón, 12002 Castellón de la Plana, Spain.
Mercedes SalgadoComplexo Hospitalario de Ourense, 32005 Ourense, Spain.
Ariadna Lloansí VilaAmgen S.A., 08039 Barcelona, Spain.
PERSEIDA Investigators

Funding

Amgen S.A. N/A
6 · The paper itself

Abstract

The serial analysis of cell-free DNA (cfDNA) enables minimally invasive monitoring of tumor evolution, providing continuous genetic information. PERSEIDA was an observational, prospective study assessing the cfDNA

Indexed as

cell-free DNAcolorectal cancerRAS mutationssolid biopsy

Identifiers

PMID36551560
PMCPMC9776941

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.