Evidence map›Paper›PMID 36551437›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Biosynthesised Silver Nanoparticles Loading onto Biphasic Calcium Phosphate for Antibacterial and Bone Tissue Engineering Applications.

Varun Prasath Padmanabhan, Pugalmani Sivashanmugam, Ravichandran Kulandaivelu, Suresh Sagadevan, Balu Sridevi, Rajakumar Govindasamy, Muthu Thiruvengadam

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Green Antimicrobials.Antibiotics (Basel, Switzerland) · 2023
    Article
  8. Green Synthesis of Magnesium Oxide Nanoparticles by UsingBioengineering (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Varun Prasath PadmanabhanDepartment of Analytical Chemistry, University of Madras, Guindy Campus, Tamil Nadu, Chennai 600025, India.
Pugalmani SivashanmugamDepartment of Orthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Tamil Nadu, Chennai 600077, India.
Ravichandran KulandaiveluDepartment of Analytical Chemistry, University of Madras, Guindy Campus, Tamil Nadu, Chennai 600025, India.
Suresh SagadevanNanotechnology & Catalysis Research Centre, University of Malaya, Kuala Lumpur 50603, Malaysia.
Balu SrideviDepartment of Electronics and Communication Engineering, Velammal Institute of Technology, Ponneri, Tamil Nadu, Thiruvallur 601204, India.
Rajakumar GovindasamyDepartment of Applied Bioscience, College of Life and Environmental Sciences, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0002-5388-5813
Muthu ThiruvengadamDepartment of Applied Bioscience, College of Life and Environmental Sciences, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0003-0986-5484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biphasic calcium phosphate (BCP) serves as one of the substitutes for bone as it consists of an intimate mixture of beta-tricalcium phosphate (β-TCP) and hydroxyapatite (HAP) in different ratios. BCP, because of its inbuilt properties such as osteoconductivity, biocompatibility, and biostability in several clinical models serves as a bone substituent for orthopedic applications. Therefore, the present study aimed to assess the effectiveness of silver (Ag) nanoparticles (NPs) combined with BCP composites for the orthopedic sector of bone tissue regeneration and growth. In this regard, we first synthesized Ag-BCP microclusters by the double-emulsion method and then characterized the composite for various physicochemical properties, including the crystallinity and crystal structure, bonding and functionality, porosity, morphology, surface charges, topography, and thermal stability. In addition, the antibacterial activity of Ag-BCP was tested against gram-positive and gram-negative microorganisms such as

Indexed as

Ag nanoparticlesantibacterial activitybiphasic calcium phosphatehydroxyapatiteMTT assayβ-tricalcium phosphate

Identifiers

PMID36551437
PMCPMC9774414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.