Evidence map›Paper›PMID 36551203›Full record

ReviewBiomolecules2022

Ribose Intake as Food Integrator: Is It a Really Convenient Practice?

Roberta Moschini, Francesco Balestri, Mario Cappiello, Giovanni Signore, Umberto Mura, Antonella Del-Corso

Abstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Roberta MoschiniBiochemistry Unit, Department of Biology, University of Pisa, Via San Zeno, 51, 56127 Pisa, Italy.ORCID 0000-0001-5227-2348
Francesco BalestriBiochemistry Unit, Department of Biology, University of Pisa, Via San Zeno, 51, 56127 Pisa, Italy.
Mario CappielloBiochemistry Unit, Department of Biology, University of Pisa, Via San Zeno, 51, 56127 Pisa, Italy.ORCID 0000-0002-8864-5043
Giovanni SignoreBiochemistry Unit, Department of Biology, University of Pisa, Via San Zeno, 51, 56127 Pisa, Italy.ORCID 0000-0002-0067-2240
Umberto MuraBiochemistry Unit, Department of Biology, University of Pisa, Via San Zeno, 51, 56127 Pisa, Italy.ORCID 0000-0001-8280-6275
Antonella Del-CorsoBiochemistry Unit, Department of Biology, University of Pisa, Via San Zeno, 51, 56127 Pisa, Italy.ORCID 0000-0003-3165-6128

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reports concerning the beneficial effects of D-ribose administration in cardiovascular and muscle stressful conditions has led to suggestions for the use of ribose as an energizing food supplement for healthy people. However, this practice still presents too many critical issues, suggesting that caution is needed. In fact, there are many possible negative effects of this sugar that we believe are underestimated, if not neglected, by the literature supporting the presentation of the product to the market. Here, the risks deriving from the use of free ribose as ATP source, forcing ribose-5-phosphate to enter into the pentose phosphate pathway, is emphasized. On the basis of the remarkable glycation capacity of ribose, the easily predictable cytotoxic effect of the molecule is also highlighted.

Indexed as

Pentose Phosphate PathwayRiboseHumansRiboseprotein glycationriboseribose-5-phosphateribose intake

Identifiers

PMID36551203
PMCPMC9776227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.