Evidence map›Paper›PMID 36551148›Full record

ReviewBiosensors2022

Recent Development of Fluorescent Nanodiamonds for Optical Biosensing and Disease Diagnosis.

Shahzad Ahmad Qureshi, Wesley Wei-Wen Hsiao, Lal Hussain, Haroon Aman, Trong-Nghia Le, Muhammad Rafique

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Widefield Diamond Quantum Sensing with Neuromorphic Vision Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  14. Luminescence Thermometry with Nanoparticles: A Review.Nanomaterials (Basel, Switzerland) · 2023
    Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Shahzad Ahmad QureshiDepartment of Computer and Information Sciences, Pakistan Institute of Engineering and Applied Sciences (PIEAS), Islamabad 45650, Pakistan.ORCID 0000-0001-8213-1431
Wesley Wei-Wen HsiaoDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan.ORCID 0000-0002-1346-327X
Lal HussainDepartment of Computer Science and Information Technology, King Abdullah Campus Chatter Kalas, University of Azad Jammu and Kashmir, Muzaffarabad 13100, Pakistan.
Haroon AmanSchool of Mathematics and Physics, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0001-6269-654X
Trong-Nghia LeInstitute of Atomic and Molecular Sciences, Academia Sinica, Taipei 106, Taiwan.ORCID 0000-0002-1841-0310
Muhammad RafiqueDepartment of Physics, King Abdullah Campus Chatter Kalas, University of Azad Jammu and Kashmir, Muzaffarabad 13100, Pakistan.ORCID 0000-0002-5216-9380
Pakistan Institute of Engineering and Applied Sciences · PKUniversity of Azad Jammu and Kashmir · PKInstitute of Atomic and Molecular Sciences, Academia Sinica · TWNational Taiwan University of Science and Technology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to precisely monitor the intracellular temperature directly contributes to the essential understanding of biological metabolism, intracellular signaling, thermogenesis, and respiration. The intracellular heat generation and its measurement can also assist in the prediction of the pathogenesis of chronic diseases. However, intracellular thermometry without altering the biochemical reactions and cellular membrane damage is challenging, requiring appropriately biocompatible, nontoxic, and efficient biosensors. Bright, photostable, and functionalized fluorescent nanodiamonds (FNDs) have emerged as excellent probes for intracellular thermometry and magnetometry with the spatial resolution on a nanometer scale. The temperature and magnetic field-dependent luminescence of naturally occurring defects in diamonds are key to high-sensitivity biosensing applications. Alterations in the surface chemistry of FNDs and conjugation with polymer, metallic, and magnetic nanoparticles have opened vast possibilities for drug delivery, diagnosis, nanomedicine, and magnetic hyperthermia. This study covers some recently reported research focusing on intracellular thermometry, magnetic sensing, and emerging applications of artificial intelligence (AI) in biomedical imaging. We extend the application of FNDs as biosensors toward disease diagnosis by using intracellular, stationary, and time-dependent information. Furthermore, the potential of machine learning (ML) and AI algorithms for developing biosensors can revolutionize any future outbreak.

Indexed as

Biosensing TechniquesNanodiamondsThermometryArtificial IntelligenceLuminescencePolymersNanodiamondsPolymersbiomarker detectionfluorescent nanodiamondsintracellular thermometrymachine learningnanoscale magnetometrynanosensorsultrasensitive biosensing

Identifiers

PMID36551148
PMCPMC9775945
OpenAlexW4312195764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.