Evidence map›Paper›PMID 36551129›Full record

ReviewBiosensors2022

Recent Advances in Electrochemical Biosensors for Monitoring Animal Cell Function and Viability.

Kyeong-Mo Koo, Chang-Dae Kim, Fu Nan Ju, Huijung Kim, Cheol-Hwi Kim, Tae-Hyung Kim

Abstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kyeong-Mo KooSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID 0000-0003-1216-8997
Chang-Dae KimSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID 0000-0003-2262-5653
Fu Nan JuSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea.
Huijung KimSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea.
Cheol-Hwi KimSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea.
Tae-Hyung KimSchool of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID 0000-0003-3671-3830

Funding

Chung-Ang University Young Scientist Scholarship Chung-Ang University Young Scientist Scholarship in 2019Ministry of Health and Welfare RS 2022 00070316National Research Foundation of Korea NRF-2022R1A4A2000776
6 · The paper itself

Abstract

Redox reactions in live cells are generated by involving various redox biomolecules for maintaining cell viability and functions. These qualities have been exploited in the development of clinical monitoring, diagnostic approaches, and numerous types of biosensors. Particularly, electrochemical biosensor-based live-cell detection technologies, such as electric cell-substrate impedance (ECIS), field-effect transistors (FETs), and potentiometric-based biosensors, are used for the electrochemical-based sensing of extracellular changes, genetic alterations, and redox reactions. In addition to the electrochemical biosensors for live-cell detection, cancer and stem cells may be immobilized on an electrode surface and evaluated electrochemically. Various nanomaterials and cell-friendly ligands are used to enhance the sensitivity of electrochemical biosensors. Here, we discuss recent advances in the use of electrochemical sensors for determining cell viability and function, which are essential for the practical application of these sensors as tools for pharmaceutical analysis and toxicity testing. We believe that this review will motivate researchers to enhance their efforts devoted to accelerating the development of electrochemical biosensors for future applications in the pharmaceutical industry and stem cell therapeutics.

Indexed as

Biosensing TechniquesNanostructuresAnimalsElectrochemical TechniquesElectrodesPotentiometryTechnologyanticancer assessmentelectrochemical biosensorlive-cell detectionstem cell differentiation monitoring

Identifiers

PMID36551129
PMCPMC9775431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.