Evidence map›Paper›PMID 36551111›Full record

ArticleBiosensors2022

Template Free Anisotropically Grown Gold Nanocluster Based Electrochemical Immunosensor for Ultralow Detection of Cardiac Troponin I.

Sumaya Nisar, Chansi, Ashish Mathur, Tinku Basu, Kshitij Rb Singh, Jay Singh

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Advancements in biosensors for cancer detection: revolutionizing diagnostics.Medical oncology (Northwood, London, England) · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sumaya NisarIndian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, Delhi, India.
ChansiAmity Centre for Nanomedicine, Amity University, Noida 201301, Uttar Pradesh, India.
Ashish MathurCentre for Interdisciplinary Research and Innovation (CIDRI), University of Petroleum and Energy Studies (UPES), Dehradun 248007, Uttarakhan, India.ORCID 0000-0002-5365-5807
Tinku BasuAmity Centre for Nanomedicine, Amity University, Noida 201301, Uttar Pradesh, India.
Kshitij Rb SinghDepartment of Chemistry, Institute of Science, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India.ORCID 0000-0002-7846-0010
Jay SinghDepartment of Chemistry, Institute of Science, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India.ORCID 0000-0002-3793-0450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anisotropic gold nanostructures have fascinated with their exceptional electronic properties, henceforth exploited for the fabrication of electrochemical sensors. However, their synthesis approaches are tedious and often require a growth template. Modern lifestyle has caused an upsurge in the risk of heart attack and requires urgent medical attention. Cardiac troponin I can serve as a biomarker in identification of suspected myocardial infection (heart attack). Hence the present work demonstrates the fabrication of a sensing platform developed by assimilating anisotropic gold nanoclusters (AuNCs) with anti cTnI antibody (acTnI) for the detection of cardiac troponin I (cTnI). The uniqueness and ease of synthesis by a template-free approach provides an extra edge for the fabrication of AuNC coated electrodes. The template-free growth of anisotropic AuNCs onto the indium tin oxide (ITO) glass substrates offers high sensitivity (2.2 × 10

Indexed as

Biosensing TechniquesMetal NanoparticlesMyocardial InfarctionElectrochemical TechniquesElectrodesGoldHumansImmunoassayLimit of DetectionTroponin IGoldTroponin Ibiosensorscardiac troponin-Igold nanoclusters (AuNCs)heart attack managementimmunosensors

Identifiers

PMID36551111
PMCPMC9775497

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.