Evidence map›Paper›PMID 36551085›Full record

ReviewBiosensors2022

Recent Advances in the Immunoassays Based on Nanozymes.

Lu Zhou, Yifan Liu, Yang Lu, Peirong Zhou, Lianqin Lu, Han Lv, Xin Hai

Abstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lu ZhouCollege of Chemistry and Chemical Engineering, Research Center for Intelligent and Wearable Technology, Qingdao University, Qingdao 266071, China.
Yifan LiuCollege of Chemistry and Chemical Engineering, Research Center for Intelligent and Wearable Technology, Qingdao University, Qingdao 266071, China.
Yang LuCollege of Chemistry and Chemical Engineering, Research Center for Intelligent and Wearable Technology, Qingdao University, Qingdao 266071, China.
Peirong ZhouCollege of Chemistry and Chemical Engineering, Research Center for Intelligent and Wearable Technology, Qingdao University, Qingdao 266071, China.
Lianqin LuCollege of Chemistry and Chemical Engineering, Research Center for Intelligent and Wearable Technology, Qingdao University, Qingdao 266071, China.
Han LvCollege of Chemistry and Chemical Engineering, Research Center for Intelligent and Wearable Technology, Qingdao University, Qingdao 266071, China.
Xin HaiCollege of Chemistry and Chemical Engineering, Research Center for Intelligent and Wearable Technology, Qingdao University, Qingdao 266071, China.

Funding

China Postdoctoral Science Foundation 2020M671988National College Students' Innovation and Entrepreneurship Training Program 202211065055National Natural Science Foundation of China 22004077
6 · The paper itself

Abstract

As a rapid and simple method for the detection of multiple targets, immunoassay has attracted extensive attention due to the merits of high specificity and sensitivity. Notably, enzyme-linked immunosorbent assay (ELISA) is a widely used immunoassay, which can provide high detection sensitivity since the enzyme labels can promote the generation of catalytically amplified readouts. However, the natural enzyme labels usually suffer from low stability, high cost, and difficult storage. Inspired by the advantages of superior and tunable catalytic activities, easy preparation, low cost, and high stability, nanozymes have arisen to replace the natural enzymes in immunoassay; they also possess equivalent sensitivity and selectivity, as well as robustness. Up to now, various kinds of nanozymes, including mimic peroxidase, oxidase, and phosphatase, have been incorporated to construct immunosensors. Herein, the development of immunoassays based on nanozymes with various types of detection signals are highlighted and discussed in detail. Furthermore, the challenges and perspectives of the design of novel nanozymes for widespread applications are discussed.

Indexed as

Biosensing TechniquesNanostructuresCatalysisEnzyme-Linked Immunosorbent AssayImmunoassayPeroxidasePeroxidaseimmunoassaysnanozymessignal amplificationtarget detection

Identifiers

PMID36551085
PMCPMC9776222

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.