Evidence map›Paper›PMID 36551070›Full record

ArticleBiosensors2022

Detection of Trace Amounts of Water in Organic Solvents by DNA-Based Nanomechanical Sensors.

Tomohiro Murata, Kosuke Minami, Tomohiko Yamazaki, Genki Yoshikawa, Katsuhiko Ariga

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Determination of water in organic solvents by ligand-exchange reaction of Tris(2-methyl-8-quinolinolato)indium(III) complex.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tomohiro MurataGraduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa 277-8561, Japan.
Kosuke MinamiCenter for Functional Sensor & Actuator (CFSN), Research Center for Functional Materials (RCFM), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan.ORCID 0000-0003-4145-1118
Tomohiko YamazakiResearch Center for Functional Materials (RCFM), National Institute for Materials Science (NIMS), 1-2-1 Sengen, Tsukuba 305-0047, Japan.ORCID 0000-0003-2136-8042
Genki YoshikawaCenter for Functional Sensor & Actuator (CFSN), Research Center for Functional Materials (RCFM), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba 305-0044, Japan.ORCID 0000-0002-9136-8964
Katsuhiko ArigaGraduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa 277-8561, Japan.ORCID 0000-0002-2445-2955
National Institute for Materials Science · JPHokkaido University · JPUniversity of Tsukuba · JP

Funding

Cabinet Office PRISMJapan Society for the Promotion of Science 18H04168Japan Society for the Promotion of Science 20H00392Japan Society for the Promotion of Science 20K05345Japan Society for the Promotion of Science 20K20554Japan Society for the Promotion of Science 21H01971Japan Society for the Promotion of Science 21K18859Japan Society for the Promotion of Science 22K05324Japan Society for the Promotion of Science JP19KK0141Japan Society for the Promotion of Science JPMJSP2108
6 · The paper itself

Abstract

The detection of trace amounts of water in organic solvents is of great importance in the field of chemistry and in the industry. Karl Fischer titration is known as a classic method and is widely used for detecting trace amounts of water; however, it has some limitations in terms of rapid and direct detection because of its time-consuming sample preparation and specific equipment requirements. Here, we found that a DNA-based nanomechanical sensor exhibits high sensitivity and selectivity to water vapor, leading to the detection and quantification of trace amounts of water in organic solvents as low as 12 ppm in THF, with a ppb level of LoD through their vapors. Since the present method is simple and rapid, it can be an alternative technique to the conventional Karl Fischer titration.

Indexed as

SolventsSolventsDNAmembrane-type surface stress sensor (MSS)nanomechanical sensorstrace amounts of water in organic solventwater detection

Identifiers

PMID36551070
PMCPMC9775023
OpenAlexW4311053638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.