Aptamer-Based Gold Nanoparticles-PDMS Composite Stamps as a Platform for Micro-Contact Printing.

Amna Didar Abbasi, Zakir Hussain, Kun-Lin Yang

Abstract read

In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Amna Didar AbbasiDepartment of Materials Engineering, School of Chemical and Materials Engineering (SCME), National University of Sciences and Technology (NUST), Islamabad 44000, Pakistan.

Zakir HussainDepartment of Materials Engineering, School of Chemical and Materials Engineering (SCME), National University of Sciences and Technology (NUST), Islamabad 44000, Pakistan.ORCID 0000-0003-4850-362X

Kun-Lin YangDepartment of Chemical and Biomolecular Engineering, National University of Singapore, Engineering Drive 4, Singapore 117576, Singapore.

Funding

Higher Education Commission P.I.N.: 315-3443-2EG3-056

6 · The paper itself

Abstract

In the present study, a functional template made up of in situ synthesised gold nanoparticles (AuNPs) is prepared on polydimethylsiloxane (PDMS) for patterning of target protein onto the desired solid substrates. Unlike previous studies in which bioreceptor probes are randomly attached to the PDMS stamp through electrostatic interactions, herein, we propose an AuNPs-PDMS stamp, which provides a surface for the attachment of thiol-modified biorecognition probes to link to the stamp surface through a dative bond with a single anchoring point based on thiol chemistry. By using this platform, we have developed the ability for microcontact printing (µCP) to selectively capture and transfer target protein onto solid surfaces for detection purposes. After µCP, we also investigated whether liquid crystals (LCs) could be used as a label-free approach for identifying transfer protein. Our reported approach provides promise for biosensing of various analytes.

Indexed as

GoldMetal NanoparticlesDimethylpolysiloxanesOligonucleotidesProteinsbaysilonDimethylpolysiloxanesGoldOligonucleotidesProteinsAuNPs–PDMS compositeDMOAPliquid crystalsmicro-contact printing

Identifiers

PMID36551034

DOI10.3390/bios12121067

PMCPMC9775676

What OpenQuestion holds

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.