ArticleBioengineering (Basel, Switzerland)2022
Mechanical Characteristics and Bioactivity of Nanocomposite Hydroxyapatite/Collagen Coated Titanium for Bone Tissue Engineering.
Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Beyond Reinforcement: Collagen-Inorganic Composites as a Roadmap for Next-Generation Biomaterials.ACS materials Au · 2026Review
- Hydroxyapatite-cellulose composites: properties, fabrication methods, and applications.Journal of materials science. Materials in medicine · 2026Review
- Graded Hydroxyapatite Triply Periodic Minimal Surface Structures for Bone Tissue Engineering Applications.Advanced healthcare materials · 2025Article
- Development of Hydroxyapatite Coatings for Orthopaedic Implants from Colloidal Solutions: Part 1-Effect of Solution Concentration and Deposition Kinetics.Nanomaterials (Basel, Switzerland) · 2023Article
- Synthesis and Characterization of a Titanium-Based Functionally Graded Material-Structured Biocomposite using Powder Metallurgy.ACS omega · 2023Article
- Three-dimensional (3D) printing in dental practice: Applications, areas of interest, and level of evidence.Clinical oral investigations · 2023Review
- Tissue Engineering Strategies Applied in Bone Regeneration and Bone Repair.Bioengineering (Basel, Switzerland) · 2023Article
- Progress in Surface Modification of Titanium Implants by Hydrogel Coatings.Gels (Basel, Switzerland) · 2023Review
- New Paradigm in Diabetic Foot Ulcer Grafting Techniques Using 3D-Bioprinted Autologous Minimally Manipulated Homologous Adipose Tissue (3D-AMHAT) with Fibrin Gel Acting as a Biodegradable Scaffold.Gels (Basel, Switzerland) · 2023Article
- Four-Dimensional Printing and Shape Memory Materials in Bone Tissue Engineering.International journal of molecular sciences · 2023Review
- Construction of functional surfaces for dental implants to enhance osseointegration.Frontiers in bioengineering and biotechnology · 2023Review
- Personalized Orbital Fracture Repair: Enhancing 3D-Printed Titanium Mesh with Biomimetic 3D-Printed HAP-COL Frameworks.Romanian journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
In the present study, we have analyzed the mechanical characteristics and bioactivity of titanium coating with hydroxyapatite/bovine collagen. Hydroxyapatite (HAp) was synthesized from a Pinctada maxima shell and has a stoichiometry (Ca/P) of 1.72 and a crystallinity of 92%, suitable for coating materials according to ISO and Food and Drug Administration (FDA) standards. Titanium (Ti) substrate coatings were fabricated at HAp concentrations of 1% (Ti/HAp-1) and 3% (Ti/HAp-3) and a bovine collagen concentration of 1% (Ti/HAp/Coll) by the electrophoresis deposition (EPD) method. The compressive strength of Ti/HAp-1 and Ti/HAp-3 was 87.28 and 86.19 MPa, respectively, and it increased significantly regarding the control/uncoated Ti (46.71 MPa). Furthermore, the Ti/HAp-coll (69.33 MPa) has lower compressive strength due to collagen substitution (1%). The bioactivity of Ti substrates after the immersion into simulated body fluids (SBF) for 3-10 days showed a high apatite growth (Ca
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.