ReviewBioengineering (Basel, Switzerland)2022
The Safety and Effectiveness of Early, Progressive Weight Bearing and Implant Choice after Traumatic Lower Extremity Fracture: A Systematic Review.
Review in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- Exploring the Effectiveness of "Four-Point" Configuration Cannulated Compression Screw Implantation Protocol for the Fixation of Pauwels Type III Femoral Neck Fractures in Adults.Orthopaedic surgery · 2026Article
- An age-related computational framework for predicting tibial fracture healing under walking rehabilitation: a comparison between younger and older adults.Medical & biological engineering & computing · 2026Article
- Biomechanical evaluation of X-ray permeable CF/PEEK composite versus conventional titanium alloy for tibial external fixation plates: a finite element analysis.Scientific reports · 2026Article
- Plate-tensioned reconstruction nail for proximal femur diaphyseal nonunion.OTA international : the open access journal of orthopaedic trauma · 2026Article
- A Traumatic Loss of the Calcaneus and Heel Pad From a Lawnmower Injury in a Pediatric Patient: A Case Report.Cureus · 2026Article
- Immediate full weightbearing with additive cerclage improves early mobility after tibial shaft spiral fractures.Scientific reports · 2025Article
- Lower incidence of new onset depressive mood disorders associated with early postoperative weight-bearing versus non-weight bearing following fixation of femur and tibia fractures.Archives of orthopaedic and trauma surgery · 2025Article
- The feasibility, acceptability, safety, and effects of early weight bearing in humeral fractures - a scoping review.Disability and rehabilitation · 2025Article
- Rehabilitation of a Professional Ballerina Post-Traumatic Fourth Toe Fracture: A Case Report.International journal of sports physical therapy · 2025Article
- Early rehabilitation nursing prevents postoperative DVT and promotes limb function recovery in patients with traumatic fracture.American journal of translational research · 2025Article
- Comparative Study of Exchange Nailing and Augmentative Plating for Treating Aseptic Nonunion of Femoral Shafts Post Intramedullary Nailing: A Single-Blind, Multicentric Randomized Clinical Trial.Journal of clinical medicine · 2024Article
- Femoral insufficiency fracture related to bisphosphonate use.Radiology case reports · 2024Article
- Weight-bearing Guidelines for Common Geriatric Upper and Lower Extremity Fractures.Current osteoporosis reports · 2023Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The goal of this systematic review was to examine existing evidence on the effectiveness of early, progressive weight bearing on patients after traumatic lower extremity fractures and relate these findings to device/implant choice. A search of the literature in PubMed/Medline, Embase, Web of Science, and the Cochrane Library was performed through January 2022. Randomized controlled trials and non-randomized, prospective longitudinal investigations of early, progressive weight bearing in skeletally mature adults after traumatic lower extremity fracture were included in the search, with 21 publications included in the final analysis. A summary of the loading progressions used in each study, along with the primary and additional outcomes, is provided. The progression of weight bearing was variable, dependent on fracture location and hardware fixation; however, overall outcomes were good with few complications. Most studies scored "high" on the bias tools and were predominately performed without physical therapist investigators. Few studies have investigated early, progressive weight bearing in patients after traumatic lower extremity fractures. The available clinical evidence provides variable progression guidelines. Relatively few complications and improved patient function were observed in this review. More research is needed from a rehabilitation perspective to obtain graded progression recommendations, informed by basic science concepts and tissue loading principles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.