Evidence map›Paper›PMID 36550934›Full record

ArticleBioengineering (Basel, Switzerland)2022

Bilateral Sensorimotor Cortical Communication Modulated by Multiple Hand Training in Stroke Participants: A Single Training Session Pilot Study.

Jian-Jia Huang, Yu-Cheng Pei, Yi-Yu Chen, Shen-Shiou Tseng, Jen-Wen Hung

4 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06070987 nacompletednot on this mapstarted 2023, after this paper: background citation

To Estimate the Efficacy of Botulinum Toxin A Injection Combing With Exoskeleton Robotic Assisted Gait Training in Stroke Patients With Spastic Stiff Knee Gait: Motor Function Performance and Neurophysiological Evaluation

TypeinterventionalSponsorChang Gung Memorial HospitalRan2023 to 2025Enrolled30ConditionsSpastic Gait, SpasticArmsBoNT-A injections, RF BoNT-A injection in first period and robot therapy, RF BoNT-A injection in second period and robot therapy
NCT06209632 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Mirror Therapy Combined With Contralaterally Controlled Functional Electrical Stimulation on Functional Recovery and Neuroplasticity in Patients With Peripheral Nerve Injury

TypeinterventionalSponsorNational Taiwan University HospitalRan2024 to 2025Enrolled7ConditionsPeripheral Nerve InjuryArmsmirror therapy, contralaterally controlled functional electrical stimulation, conventional physiotherapy
NCT07054424 narecruitingnot on this mapstarted 2025, after this paper: background citation

Development of Repetitive Transcranial Magnetic Stimulation (rTMS) Combined With Machine-assisted Bimanual Therapy (BT) in Upper Limb Rehabilitation

TypeinterventionalSponsorChang Gung Memorial HospitalRan2025 to 2027Enrolled54ConditionsPost-stroke Upper Limb Hemiparesis, Repetitive Transcranial Magnetic Stimulation (rTMS), Bimanual Therapy, NeuromodulationArmsConventional occupation therapy, stretching exercise, rTMS, bimanual therapy
NCT07080099 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Bimanual Intensive Therapy With Sensory Training on Motor Function, Sensory Function and Functional Independence in Post Stroke Patients

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2024Enrolled38ConditionsStrokeArmsBIMANUAL INTENSIVE THERAPY WITH PASSIVE SENSORY TRAINING, BIMANUAL INTENSIVE THERAPY WITH ACTIVE SENSORY TRAINING
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jian-Jia HuangDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, Taoyuan City 333, Taiwan.ORCID 0000-0002-9796-9744
Yu-Cheng PeiDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, Taoyuan City 333, Taiwan.ORCID 0000-0001-5986-0046
Yi-Yu ChenDepartment of Rehabilitation, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan.
Shen-Shiou TsengDepartment of Physical Medicine and Rehabilitation, Tao-Yuan General Hospital, Taoyuan City 330, Taiwan.
Jen-Wen HungDepartment of Rehabilitation, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan.
Chang Gung University · TWKaohsiung Chang Gung Memorial Hospital · TWTao Yuan General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bi-manual therapy (BT), mirror therapy (MT), and robot-assisted rehabilitation have been conducted in hand training in a wide range of stages in stroke patients; however, the mechanisms of action during training remain unclear. In the present study, participants performed hand tasks under different intervention conditions to study bilateral sensorimotor cortical communication, and EEG was recorded. A multifactorial design of the experiment was used with the factors of manipulating objects (O), robot-assisted bimanual training (RT), and MT. The sum of spectral coherence was applied to analyze the C3 and C4 signals to measure the level of bilateral corticocortical communication. We included stroke patients with onset <6 months (n = 6), between 6 months and 1 year (n = 14), and onset >1 year (n = 20), and their Brunnstrom recovery stage ranged from 2 to 4. The results showed that stroke duration might influence the effects of hand rehabilitation in bilateral cortical corticocortical communication with significant main effects under different conditions in the alpha and beta bands. Therefore, stroke duration may influence the effects of hand rehabilitation on interhemispheric coherence.

Indexed as

bimanual trainingcoherenceEEGmirror therapyrobot-assisted trainingsensorimotor cortexstroke

Identifiers

PMID36550934
PMCPMC9774770
OpenAlexW4310037513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.