Evidence map›Paper›PMID 36550556›Full record

Observational studyJournal of cardiothoracic surgery2022

Effect of mechanical ventilation during cardiopulmonary bypass on end-expiratory lung volume in the perioperative period of cardiac surgery: an observational study.

Léa Trancart, Nathalie Rey, Vincent Scherrer, Véronique Wurtz, Fabrice Bauer, Chadi Aludaat, Zoe Demailly, Jean Selim, Vincent Compère, Thomas Clavier and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of cardiothoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Léa TrancartDepartment of Anaesthesiology and Critical Care, CHU Rouen, 76031, Rouen, France.
Nathalie ReyDepartment of Anaesthesiology and Critical Care, CHU Rouen, 76031, Rouen, France.
Vincent ScherrerDepartment of Anaesthesiology and Critical Care, CHU Rouen, 76031, Rouen, France.
Véronique WurtzDepartment of Anaesthesiology and Critical Care, CHU Rouen, 76031, Rouen, France.
Fabrice BauerDepartment of Cardiac Surgery, CHU Rouen, 76031, Rouen, France.
Chadi AludaatDepartment of Cardiac Surgery, CHU Rouen, 76031, Rouen, France.
Zoe DemaillyDepartment of Anaesthesiology and Critical Care, CHU Rouen, 76031, Rouen, France.
Jean SelimDepartment of Anaesthesiology and Critical Care, CHU Rouen, 76031, Rouen, France.
Vincent CompèreDepartment of Anaesthesiology and Critical Care, CHU Rouen, 76031, Rouen, France.
Thomas ClavierDepartment of Anaesthesiology and Critical Care, CHU Rouen, 76031, Rouen, France.
Emmanuel BesnierDepartment of Anaesthesiology and Critical Care, CHU Rouen, 76031, Rouen, France. Emmanuel.besnier@chu-rouen.fr.ORCID http://orcid.org/0000-0002-0267-0986

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany studies explored the impact of ventilation during cardiopulmonary bypass (CPB) period with conflicting results. Functional residual capacity or End Expiratory Lung Volume (EELV) may be disturbed after cardiac surgery but the specific effects of CPB have not been studied. Our objective was to compare the effect of two ventilation strategies during CPB on EELV.

methodsObservational single center study in a tertiary teaching hospital. Adult patients undergoing on-pump cardiac surgery by sternotomy were included. Maintenance of ventilation during CPB was left to the discretion of the medical team, with division between "ventilated" and "non-ventilated" groups afterwards. Iterative intra and postoperative measurements of EELV were carried out by nitrogen washin-washout technique. Main endpoint was EELV at the end of surgery. Secondary endpoints were EELV one hour after ICU admission, PaO

resultsForty consecutive patients were included, 20 in each group. EELV was not significantly different between the ventilated versus non-ventilated groups at the end of surgery (1796 ± 586 mL vs. 1844 ± 524 mL, p = 1) and one hour after ICU admission (2095 ± 562 vs. 2045 ± 476 mL, p = 1). No significant difference between the two groups was observed on PaO

conclusionNo significant difference was observed in EELV after cardiac surgery between not ventilated and ventilated patients during CPB.

Indexed as

Cardiac Surgical ProceduresRespiration, ArtificialAdultCardiopulmonary BypassHumansLungLung Volume MeasurementsPerioperative PeriodPostoperative ComplicationsCardiac surgeryCardiopulmonary bypassFunctional residual capacityLung volume measurementVentilation

Identifiers

PMID36550556
PMCPMC9784092

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.