Evidence map›Paper›PMID 36550475›Full record

ArticleBMC pulmonary medicine2022

Validity and repeatability of cardiopulmonary exercise testing in interstitial lung disease.

Owen W Tomlinson, Laura Markham, Rebecca L Wollerton, Bridget A Knight, Anna Duckworth, Michael A Gibbons, Chris J Scotton, Craig A Williams

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06141603 unknown statusnot on this mapstarted 2023, after this paper: background citation

Comparison of Upper and Lower Limb Maximal Exercise Capacities, Muscle Oxygenation and Energy Consumption During Tests in Patients With Interstitial Lung Disease

TypeobservationalSponsorGazi UniversityRan2023 to 2024Enrolled30ConditionsInterstitial Lung Disease
NCT07315425 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Investigation of the Acute Effects of Blood Flow Restriction Aerobic Exercise on Hemodynamic Responses and Muscle Oxygen in Patients With Interstitial Lung Disease

TypeinterventionalSponsorGazi UniversityRan2026 to 2028Enrolled30ConditionsInterstitial Lung Disease (ILD)ArmsBlood flow restriction (BFR) low-intensity aerobic exercise training, Low-intensity aerobic exercise training
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Owen W TomlinsonDepartment of Public Health and Sports Sciences, Faculty of Health and Life Sciences, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK.
Laura MarkhamAcademic Department of Respiratory Medicine, Royal Devon University Healthcare NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK.
Rebecca L WollertonAcademic Department of Respiratory Medicine, Royal Devon University Healthcare NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK.
Bridget A KnightDepartment of Clinical and Biomedical Science, Faculty of Health and Life Sciences, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK.
Anna DuckworthDepartment of Clinical and Biomedical Science, Faculty of Health and Life Sciences, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK.
Michael A GibbonsAcademic Department of Respiratory Medicine, Royal Devon University Healthcare NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK.
Chris J ScottonDepartment of Clinical and Biomedical Science, Faculty of Health and Life Sciences, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK.
Craig A WilliamsDepartment of Public Health and Sports Sciences, Faculty of Health and Life Sciences, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK. c.a.williams@exeter.ac.uk.
University of Exeter · GBRoyal Devon & Exeter NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiopulmonary exercise testing (CPET), and its primary outcome of peak oxygen uptake (VO

methodsTwenty-six people with ILD were recruited, and 21 successfully completed three CPETs. Of these, 17 completed two valid CPETs within a 3-month window, and 11 completed two valid CPETs within a 6-month window. Technical standards from the European Respiratory Society established validity, and repeatability was determined using mean change, intraclass correlation coefficient and typical error.

resultsEvery participant (100%) who successfully exercised to volitional exhaustion produced a maximal, and therefore valid, CPET. Approximately 20% of participants presented with a plateau in VO

conclusionThis work has, for the first time, fully characterised how patients with ILD respond to CPET in terms of primary and secondary verification criteria, and generated novel repeatability data that will prove useful in the assessment of disease progression, and future evaluation of therapeutic regimens where VO

Indexed as

Exercise TestLung Diseases, InterstitialHumansOxygen ConsumptionRespiratory Function TestsRespiratory Physiological PhenomenaAerobic fitnessClinical physiologyMaximal exercisePulmonary disease

Identifiers

PMID36550475
PMCPMC9784077
OpenAlexW4312190474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.