Evidence map›Paper›PMID 36550322›Full record

ArticleNature immunology2023

An αvβ3 integrin checkpoint is critical for efficient T

Aydan C H Szeto, Ana C F Ferreira, Jonathan Mannion, Paula A Clark, Meera Sivasubramaniam, Morgan W D Heycock, Alastair Crisp, Helen E Jolin, Patrycja Kozik, Martin D Knolle and 1 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. The Past, the Present, and the Future of Periostin in Allergy.Allergy, asthma & immunology research · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. The immunology of asthma.Nature immunology · 2025
    Review
  8. Calpain-2-Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. The role of IL-2 in type 2 immunity.Frontiers in immunology · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. CRISPR-Cas9 applications in T cells and adoptive T cell therapies.Cellular & molecular biology letters · 2024
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Aydan C H SzetoMRC Laboratory of Molecular Biology, Cambridge, UK. aszeto@mrc-lmb.cam.ac.uk.ORCID http://orcid.org/0000-0002-3456-2154
Ana C F FerreiraMRC Laboratory of Molecular Biology, Cambridge, UK.
Jonathan MannionMRC Laboratory of Molecular Biology, Cambridge, UK.
Paula A ClarkMRC Laboratory of Molecular Biology, Cambridge, UK.
Meera SivasubramaniamMRC Laboratory of Molecular Biology, Cambridge, UK.
Morgan W D HeycockMRC Laboratory of Molecular Biology, Cambridge, UK.
Alastair CrispMRC Laboratory of Molecular Biology, Cambridge, UK.
Helen E JolinMRC Laboratory of Molecular Biology, Cambridge, UK.
Patrycja KozikMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID http://orcid.org/0000-0001-8596-843X
Martin D KnolleMRC Laboratory of Molecular Biology, Cambridge, UK.
Andrew N J McKenzieMRC Laboratory of Molecular Biology, Cambridge, UK. anm@mrc-lmb.cam.ac.uk.ORCID http://orcid.org/0000-0001-9757-2512
MRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_EX_MR/T005386/1Medical Research Council MC_U105178805Medical Research Council MC_UP_1201/26Medical Research Council MR/T005386/1Medical Research Council U105178805Wellcome Trust 100963Wellcome Trust 100963/Z/13/ZWellcome Trust 220223Wellcome Trust 220223/Z/20/Z
6 · The paper itself

Abstract

Naive CD4

Indexed as

CytokinesTh2 CellsAllergensAnimalsCell DifferentiationLungMammalsMiceAllergensCytokines

Identifiers

PMID36550322
OpenAlexW4312114242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.