Evidence map›Paper›PMID 36550303›Full record

ReviewNature biomedical engineering2023

Opportunities and challenges in the development of exoskeletons for locomotor assistance.

Christopher Siviy, Lauren M Baker, Brendan T Quinlivan, Franchino Porciuncula, Krithika Swaminathan, Louis N Awad, Conor J Walsh

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Nature biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06602544 (Preventing Freezing of Gait in Parkinson's Disease Using Soft Robotic Apparel), which is not on this map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
16.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06602544 narecruitingnot on this mapstarted 2024, after this paper: background citation

Preventing Freezing of Gait in Parkinson's Disease Using Soft Robotic Apparel

TypeinterventionalSponsorHarvard Medical School (HMS and HSDM)Ran2024 to 2027Enrolled20ConditionsParkinson Disease (PD)ArmsRobotic Apparel
3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 211 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. PositiveAssist: Energy-Gated Control for Positive Power Assistance of Exoskeleton in Walking, Running, and Stair Climbing.IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division · 2026
    Article
  6. Article
  7. Article
  8. Article
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  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christopher Siviy *John A Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.ORCID 0000-0003-0789-0109
Lauren M Baker *John A Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
Brendan T QuinlivanJohn A Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
Franchino PorciunculaJohn A Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
Krithika SwaminathanJohn A Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
Louis N AwadDepartment of Physical Therapy, College of Health and Rehabilitation Sciences: Sargent, Boston University, Boston, MA, USA.ORCID 0000-0002-0159-8011
Conor J WalshJohn A Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA. walsh@seas.harvard.edu.ORCID 0000-0002-2744-917X
Harvard University · USBoston University · US

Funding

Development of a Modular Soft Exosuit Platform Suitable for Community-Based NeurorehabilitationR01HD088619 · NICHD · HARVARD UNIVERSITY · PI WALSH, CONOR · 2016 to 2021
$3.9M
SCH: Multimodal,Task-Aware Movement Assessment and Control: Clinic to HomeR01AG067394 · NIA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI AWAD, LOUIS N, TRON, ROBERTO · 2019 to 2022
$1.2M
NIA NIH HHS R01 AG067394NICHD NIH HHS R01 HD088619
6 · The paper itself

Abstract

Exoskeletons can augment the performance of unimpaired users and restore movement in individuals with gait impairments. Knowledge of how users interact with wearable devices and of the physiology of locomotion have informed the design of rigid and soft exoskeletons that can specifically target a single joint or a single activity. In this Review, we highlight the main advances of the past two decades in exoskeleton technology and in the development of lower-extremity exoskeletons for locomotor assistance, discuss research needs for such wearable robots and the clinical requirements for exoskeleton-assisted gait rehabilitation, and outline the main clinical challenges and opportunities for exoskeleton technology.

Indexed as

Exoskeleton DeviceGaitHumansLocomotion

Identifiers

PMID36550303
PMCPMC11536595
OpenAlexW4312115223

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.