ArticleAJNR. American journal of neuroradiology2023
Automated Estimation of Quantitative Lesion Water Uptake as a Prognostic Biomarker for Patients with Ischemic Stroke and Large-Vessel Occlusion.
Article in AJNR. American journal of neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Tmax 10 Volume Is Independently Associated with NWU Delta in Large Core Stroke.Clinical neuroradiology · 2026Observational
- Predicting futile recanalization before mechanical thrombectomy: the added value of CT imaging markers.Neuroradiology · 2025Article
- Deep learning biomarker of chronometric and biological ischemic stroke lesion age from unenhanced CT.NPJ digital medicine · 2024Article
- Role of Computed Tomography Angiography Enhancement Ratio in Predicting Prognosis in Patients With Stroke Undergoing Endovascular Treatment.Stroke (Hoboken, N.J.) · 2024Article
- Association between occlusion location, net water uptake and ischemic lesion growth in large vessel anterior circulation strokes.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Novel advanced imaging techniques for cerebral oedema.Frontiers in neurology · 2024Review
- Clinical software for unsupervised automated net water uptake analysis predicts futile recanalization in acute ischemic stroke.Frontiers in neurologyArticle
- A novel automated CT biomarker to predict outcomes in acute ischemic stroke: net water uptake.Frontiers in neurologyArticle
- Net water uptake and ASPECTS in predicting futile recanalization for acute large vessel occlusion stroke: insights from time window stratification.Frontiers in neurologyArticle
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeNet water uptake is qualified as an imaging marker of brain edema. We aimed to investigate the ability of net water uptake to predict 90-day functional outcome in patients with acute ischemic stroke and large-vessel occlusion. MATERIALS AND
methodsA total of 295 consecutive patients were retrospectively enrolled. Automated ASPECTS-net water uptake was calculated on the admission CT. The relationship between ASPECTS-net water uptake and 90-day neurologic outcome was assessed. The independent predictors of favorable outcome (mRS score ≤2) were assessed using multivariate logistic regression analysis and receiver operating characteristic curves and stratified by the ASPECTS.
resultsFavorable 90-day outcomes were observed in 156 (52.9%) patients. ASPECTS-net water uptake (OR, 0.79; 95% CI, 0.70-0.90), NIHSS scores (OR, 0.91; 95% CI, 0.87-0.96), age (OR, 0.96; 95% CI, 0.94-0.99), and vessel recanalization (OR, 7.78; 95% CI, 3.96-15.29) were independently associated with favorable outcomes at 90 days (all,
conclusionsASPECTS-net water uptake could independently predict 90-day neurologic outcomes in patients with acute ischemic stroke and large-vessel occlusion. Integrating ASPECTS-net water uptake with clinical models could improve the efficiency of outcome stratification.
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