Evidence map›Paper›PMID 36549747›Full record

ArticleBMJ open2022

Cannabis Use in Pregnancy and Downstream effects on maternal and infant health (CUPiD): a protocol for a birth cohort pilot study.

Serine Ramlawi, Malia S Q Murphy, Alysha L J Dingwall-Harvey, Ruth Rennicks White, Laura M Gaudet, Amy McGee, Amanda DeGrace, Christina Cantin, Darine El-Chaâr, Mark C Walker and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05309226 (Cannabis Use in Pregnancy and Downstream Effects on Maternal and Infant Health), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05309226 completednot on this map

Cannabis Use in Pregnancy and Downstream Effects on Maternal and Infant Health (CUPiD): A Pilot Prospective Cohort Study

TypeobservationalSponsorOttawa Hospital Research InstituteRan2022 to 2025Enrolled43ConditionsCannabis Use, Marijuana UseArmsCannabis use in pregnancy or cannabis exposure in utero
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Serine RamlawiClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID 0000-0003-4356-9726
Malia S Q MurphyClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Alysha L J Dingwall-HarveyClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Ruth Rennicks WhiteClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Laura M GaudetDepartment of Obstetrics and Gynecology, Queen's University, Kingston, Ontario, Canada.
Amy McGeeDivision of Midwifery, Ottawa Hospital, Ottawa, Ontario, Canada.
Amanda DeGraceClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Christina CantinFaculty of Health Sciences, Queen's University, Kingston, Ontario, Canada.
Darine El-ChaârClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID 0000-0002-8266-0242
Mark C WalkerClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Daniel J CorsiFaculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada dcorsi@ohri.ca.ORCID 0000-0001-7063-3354
Ottawa Hospital · CAUniversity of Ottawa · CAQueen's University · CA

Funding

CIHR CA3-170126
6 · The paper itself

Abstract

introductionCannabis use in pregnancy and post partum is increasing. Accessibility to cannabis has expanded due to the legalisation of cannabis in Canada. Therefore, there is a critical need to monitor the impact of cannabis on pregnancy outcomes and infant neurodevelopment. This pilot study will assess the feasibility of modern recruitment and data collection strategies adapted to the current cannabis environment and inform the design of a multicentre prospective birth cohort. METHODS AND ANALYSIS: We will establish a pregnancy and birth cohort of 50 cannabis users and 50 non-users recruited before delivery. We will follow the participants at regular visits from recruitment to 12 weeks post partum. Participants will provide demographic and socioeconomic data, report their cannabis use patterns, and provide biological samples. Biological samples include maternal and infant urine and blood, breastmilk/chestmilk, cord blood, cord tissue, placenta and meconium. All samples will be processed and stored at -80°C until analysis by immunoassay or liquid chromatography-tandem mass spectrometry to determine the presence of cannabis metabolites. In addition, partners will be invited to provide additional socioeconomic and substance use data. ETHICS AND DISSEMINATION: Ethics was obtained from Ottawa Health Science Network Research Ethics Board through Clinical Trials Ontario (3791). Our findings will be published in peer-reviewed journals, presented at scientific conferences and shared broadly with patients, healthcare decision-makers, and project partners online and through social media. TRIAL REGISTRATION NUMBER: NCT05309226.Cite Now.

Indexed as

CannabisBirth CohortFemaleHumansInfantInfant HealthOntarioPilot ProjectsPregnancyProspective StudiesResearch DesignEPIDEMIOLOGYFetal medicineOBSTETRICSPAEDIATRICS

Identifiers

PMID36549747
PMCPMC9791409
OpenAlexW4312190811

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.