Trial reportAddictive behaviors2023
Nicotine replacement therapy for vaping cessation among mono and dual users: A mixed methods preliminary study.
Trial report in Addictive behaviors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 6 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Vaping cessation interventions: a systematic review and meta-analysis.Tobacco control · 2026Pooled it
- A systematic review of the effectiveness, safety and acceptance of nicotine replacement therapy use for vaping cessation in youth aged 17 years or younger.Systematic reviews · 2026Pooled it
- Interventions for quitting vaping.The Cochrane database of systematic reviews · 2025Pooled it
- Korean Clinical Practice Guideline of Korean Society for Research on Nicotine and Tobacco (KSRNT) and National Evidence-based Healthcare Collaborating Agency (NECA) on Treatment of Tobacco Use 2024.Journal of Korean medical science · 2025Guideline
- Interventions for quitting vaping.The Cochrane database of systematic reviews · 2025Pooled it
- Pharmacological Interventions for Electronic Cigarette Cessation: A Systematic Review and Meta-analyses.Journal of addiction medicinePooled it
- Augmented Doses of Nicotine Replacement Therapy: Feasibility for Dual Cigarette and E-Cigarette Cessation.American journal of preventive medicine · 2025Trial
- Varenicline for E-Cigarette Cessation in Adults: A Preliminary Placebo-Controlled Randomized Trial.American journal of preventive medicine · 2024Trial
- Vaping cessation interventions: A narrative review of randomized controlled trials.Tobacco prevention & cessation · 2026Review
- Electronic Nicotine Delivery Systems (ENDS): Implications for the Clinician.Pulmonary therapy · 2025Review
- Ex-Vapers' Perspectives on Helpful and Unhelpful Influences During Their Quit Journeys.International journal of environmental research and public health · 2025Article
- Barriers and facilitators to nicotine and cannabis vaping cessation among young adults: a qualitative study using Capability, Opportunity, Motivation, and Behavior (COM-B) model and Theoretical Domains Framework (TDF).Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025Article
- Urgent need for treatment addressing co-use of tobacco and cannabis: An updated review and considerations for future interventions.Addictive behaviors · 2024Review
- Developing a Vape Shop-Based Smoking Cessation Intervention: A Delphi Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Many adults express interest in e-cigarette cessation; however, there are few empirically tested interventions for quitting vaping. This study seeks to (1) evaluate reasons for quitting e-cigarettes in treatment-seeking adults, and (2) assess the feasibility and acceptability of nicotine replacement therapy (NRT) for e-cigarette cessation. Adult daily e-cigarette users completed qualitative interviews about quitting e-cigarettes, then were randomized to either 28-day supply of combination NRT (21 mg patches, 4 mg lozenges) + supportive booklet or Quitline referral. Primary aims were feasibility (number who enrolled) and acceptability (NRT use, adverse side effects). Exploratory aims evaluated abstinence (7-day point-prevalence) at end of treatment. Of the 30 participants who were enrolled, 50 % (n = 15) were dual users, and 50 % (n = 15) were mono-vapers, 26.6 % (n = 8) of whom were former smokers. Participants reported seeking treatment due to health concerns, dependence, stigma, and cost. Anticipated challenges of quitting vaping were withdrawal, negative mood, sensorimotor habits, and convenience. Most completed the end of treatment survey (n = 24; 80 %). Participants who received NRT reported using the patch M = 10.89 days and lozenges M = 6.39 days, with few days of adverse effects (M = 2.67). At end of treatment, 6/18 (33.3 %; 6 mono and 0 dual users) in the intervention group reported abstinence from vaping, compared to 0 in the control group (Fisher = 5.00, p =.057). In conclusion, adults are interested in quitting e-cigarettes due to negative consequences of use and are willing to use pharmacotherapy. Future research should confirm these results in a larger trial, address cigarette smoking in dual users, and aim to disseminate treatments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.