Evidence map›Paper›PMID 36549097›Full record

ArticlePsychiatry research2023

Mechanism-based groups of children with ADHD are associated with distinct domains of impairment.

Zvi R Shapiro, Bethany Bray, Cynthia Huang-Pollock

Open access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Zvi R ShapiroDepartment of Psychiatry, Emory University, Atlanta, GA, USA. Electronic address: zrshapi@emory.edu.
Bethany BrayCenter for Dissemination and Implementation Science, The University of Illinois at Chicago, Chicago, IL, USA.
Cynthia Huang-PollockDepartment of Psychology, The Pennsylvania State University, State College, PA, USA.
Emory University · USPennsylvania State University · USUniversity of Illinois Chicago · US

Funding

Social and Academic Problems in ADHD: The Role of Implicit and Explicit LearningR01MH084947 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI HUANG-POLLOCK, CYNTHIA L · 2010 to 2014
$1.8M
NIMH NIH HHS R01 MH084947
6 · The paper itself

Abstract

Person-oriented analyses are commonly used to identify subgroups of children with mental health conditions in the hopes that they will meaningfully inform the taxonomy, assessment, and treatment of psychological disorder. However, whether these data-driven groups are demonstrably better at predicting important aspects of adaptive functioning than standard DSM taxonomy has not been established. Using Attention-Deficit-Hyperactivity-Disorder (ADHD) as a model condition, we utilized dimensions of personality and cognitive ability to identify person-centered profiles of school-aged children (N=246) and evaluated the association of these profiles with critical areas of adaptive functioning. A single profile ("Conscientious") represented non-ADHD controls and was characterized by faster drift rate and higher executive functioning scores. Three profiles ("Disagreeable," "Negative Emotionality," and "Extraverted") were identified for children with ADHD. Drift rate, but not executive functioning, distinguished among ADHD profiles, which were also distinctly associated with comorbid externalizing and internalizing psychopathology, social skills, and academic achievement. In contrast, the Diagnostic and Statistical Manual (DSM) presentations were not informative and showed similar patterns of impairment across domains. Person-centered profiles of children with ADHD are associated with distinct adaptive functioning deficits and may be useful in informing clinical practice.

Indexed as

Attention Deficit Disorder with HyperactivityChildCognitionComorbidityHumansMental HealthPersonality DisordersADHDAssessmentImpairmentLatent profile analysisNosology

Identifiers

PMID36549097
PMCPMC9835004
OpenAlexW4313312760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.