Evidence map›Paper›PMID 36549051›Full record

SynthesisClinical biomechanics (Bristol, Avon)2023

Comparison of clinical and biomechanical characteristics between individuals with lower limb amputation with and without lower back pain: A systematic review and meta-analysis.

Szu-Ping Lee, Shawn Farrokhi, Jenny A Kent, Jason Ciccotelli, Lung-Chang Chien, Jo Armour Smith

Open access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Clinical biomechanics (Bristol, Avon), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Szu-Ping LeeDepartment of Physical Therapy, University of Nevada, Las Vegas, NV, USA. Electronic address: szu-ping.lee@unlv.edu.
Shawn FarrokhiResearch and Surveillance Division, DoD-VA Extremity Trauma and Amputation Center of Excellence (EACE), San Antonio, TX, USA; Department of Physical and Occupational Therapy, Chiropractic Services and Sports Medicine, Naval Medical Center San Diego, San Diego, CA, USA.
Jenny A KentDepartment of Physical Therapy, University of Nevada, Las Vegas, NV, USA.
Jason CiccotelliDepartment of Physical Therapy, University of Nevada, Las Vegas, NV, USA.
Lung-Chang ChienDepartment of Epidemiology and Biostatistics, University of Nevada, Las Vegas, NV, USA.
Jo Armour SmithDepartment of Physical Therapy, Chapman University, Irvine, CA, USA.
University of Nevada, Las Vegas · USChapman University · USNaval Medical Center San Diego · US

Funding

Motor Learning in Individuals with and at risk of Lower Limb Loss: Implications for Amputee RehabilitationK01HD091449 · NICHD · UNIVERSITY OF NEVADA LAS VEGAS · PI LEE, SZU-PING · 2018 to 2022
$651k
NICHD NIH HHS K01 HD091449
6 · The paper itself

Abstract

backgroundLower back pain is a debilitating condition common to individuals with lower limb amputation. It is unclear what risk factors contribute to the development of back pain. This study systematically reviewed and analyzed the available evidence regarding the clinical and biomechanical differences between individuals with amputation, with and without lower back pain.

methodsA literature search was conducted in PubMed, Web of Science, Scopus, and CINAHL databases in November 2020 and repeated in June 2021 and June 2022. Studies were included if they reported comparisons of demographic, anthropometric, biomechanical, and other clinical variables between participants with and without LBP. Study quality and potential for reporting bias were assessed. Meta-analyses were conducted to compare the two groups.

findingsThirteen studies were included, with aggregated data from 436 participants (239 with LBP; 197 pain free). The median reporting quality score was 37.5%. The included studies enrolled participants who were predominantly male (mean = 91.4%, range = 77.8-100%) and with trauma-related amputation. Meta-analyses showed that individuals with LBP exhibited moderate (3.4 out of 10) but significantly greater pain than those without LBP. We found no between-group differences in age, height, weight, BMI, and time since amputation (p = 0.121-0.682). No significant differences in trunk/pelvic kinematics during gait were detected (p = 0.07-0.446) between the groups.

interpretationDemographic, anthropometric, biomechanical, and simple clinical outcome variables may be insufficient for differentiating the risk of developing back pain after amputation. Investigators should be aware of the existing gender bias in sampling and methodological limitations, as well as to consider incorporating psychosocial measures when studying LBP in this clinical population.

Indexed as

Low Back PainAmputation, SurgicalBiomechanical PhenomenaFemaleHumansLower ExtremityMaleRisk FactorsSexismAmputationBackacheBack painLimb lossProstheticsSpine

Identifiers

PMID36549051
PMCPMC9892268
OpenAlexW4311278004

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.