Evidence map›Paper›PMID 36548815›Full record

ArticleVeterinary sciences2022

A Pilot Study on the Urine Proteome of Cats Fed a High-Protein Complete Diet, Supplemented with or without Arginine, Ornithine or Zeolite.

Nadine Paßlack, Katharina Nöbauer, Karin Hummel, Ebrahim Razzazi-Fazeli, Vitaly Belik, Jürgen Zentek

Open access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. AData in brief · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Nadine PaßlackInstitute of Animal Nutrition, Freie Universität Berlin, 14195 Berlin, Germany.
Katharina NöbauerVetCore Facility for Research, University of Veterinary Medicine, 1210 Vienna, Austria.
Karin HummelVetCore Facility for Research, University of Veterinary Medicine, 1210 Vienna, Austria.
Ebrahim Razzazi-FazeliVetCore Facility for Research, University of Veterinary Medicine, 1210 Vienna, Austria.
Vitaly BelikInstitute for Veterinary Epidemiology and Biostatistics, Freie Universität Berlin, 14163 Berlin, Germany.ORCID 0000-0003-3748-0071
Jürgen ZentekInstitute of Animal Nutrition, Freie Universität Berlin, 14195 Berlin, Germany.
Freie Universität Berlin · DEUniversity of Veterinary Medicine Vienna · AT

Funding

almapharm GmbH + Co. KG, Germany n/a
6 · The paper itself

Abstract

Proteome analyses can be used to detect biomarkers for the healthy and diseased organism. However, data in cats are scarce, and no information is available on the potential impact of nutritional interventions on the feline urine proteome. In the present study, a label-free shotgun proteomics approach was performed to investigate the urinary proteins of four healthy adult cats. Each animal received a high-protein complete diet without (w/o) or with supplements that could affect the protein metabolism: arginine (+100% compared to the arginine concentration in the w/o diet), ornithine (+200% compared to the arginine concentration in the w/o diet) or zeolite (0.375 g/kg body weight/day). Our results demonstrate a huge number of proteins in the urine of cats (516 ± 49, 512 ± 39, 399 ± 149 and 455 ± 134 in the w/o, arginine, ornithine and zeolite group, respectively), which are associated with several biological processes. In addition, up- and downregulated urinary proteins could be detected in the dietary supplementation periods. Overall, the present pilot study provides basic data on the urine proteome of healthy adult cats. With increasing information, the numerousness of urinary proteins implies the potential to identify biomarkers and metabolic pathways in the feline organism.

Indexed as

felineliquid chromatography coupled to mass spectrometrynutritionproteomeurine

Identifiers

PMID36548815
PMCPMC9782089
OpenAlexW4309728409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.