Evidence map›Paper›PMID 36548771›Full record

ArticleToxins2022

Candidalysin Is the Hemolytic Factor of

Selene Mogavero, Sarah Höfs, Alexa N Lauer, Rita Müller, Sascha Brunke, Stefanie Allert, Franziska Gerwien, Sabrina Groth, Edward Dolk, Duncan Wilson and 2 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Hemolytic Activity of VaginalPathogens (Basel, Switzerland) · 2026
    Article
  2. [Pathophysiologically complex bilateral profound sensorineural hearing loss in the setting of type 2 diabetes mellitus and fungal sepsis: a case report].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Article
  3. Review
  4. Frontiers in fungal biology · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Host targets of candidalysin.PLoS pathogens · 2025
    Review
  9. Deletion ofmSphere · 2025
    Article
  10. Article
  11. Review
  12. Microbiology and molecular biology reviews : MMBR · 2024
    Review
  13. Article
  14. Host cell responses toFrontiers in cellular and infection microbiology · 2024
    Article
  15. A Putative Role ofMicroorganisms · 2023
    Review
  16. The Interplay betweenMicroorganisms · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Selene MogaveroDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute (HKI), 07745 Jena, Germany.ORCID 0000-0003-0642-0068
Sarah HöfsDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute (HKI), 07745 Jena, Germany.
Alexa N LauerDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute (HKI), 07745 Jena, Germany.
Rita MüllerDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute (HKI), 07745 Jena, Germany.ORCID 0000-0003-0913-9378
Sascha BrunkeDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute (HKI), 07745 Jena, Germany.ORCID 0000-0001-7740-4570
Stefanie AllertDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute (HKI), 07745 Jena, Germany.
Franziska GerwienDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute (HKI), 07745 Jena, Germany.
Sabrina GrothResearch Center Borstel, Division of Biophysics, 23845 Borstel, Germany.
Edward DolkQVQ B.V., 3584 CL Utrecht, The Netherlands.
Duncan WilsonMedical Research Council Centre for Medical Mycology, University of Exeter, Exeter EX4 4RN, UK.
Thomas GutsmannResearch Center Borstel, Division of Biophysics, 23845 Borstel, Germany.
Bernhard HubeDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute (HKI), 07745 Jena, Germany.ORCID 0000-0002-6028-0425
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DEResearch Center Borstel - Leibniz Lung Center · DEQserve Group (Netherlands) · NLUniversity of Exeter · GB

Funding

Wellcome TrustWellcome Trust 215599/Z/19/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Candida albicansHemolysisCandidaFungal ProteinsMucous MembraneVirulence FactorsFungal ProteinsVirulence FactorsCandida albicanscandidalysinerythrocyteshemolysinintercalationnanobodiesneutralizationpeptide toxinPPADSVHH

Identifiers

PMID36548771
PMCPMC9785678
OpenAlexW4311791387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.