Evidence map›Paper›PMID 36548761›Full record

ArticleToxins2022

Improving the In Vitro Removal of Indoxyl Sulfate and p-Cresyl Sulfate by Coating Diatomaceous Earth (DE) and Poly-vinyl-pyrrolidone-co-styrene (PVP-co-S) with Polydopamine.

Stefania Roberta Cicco, Maria Michela Giangregorio, Maria Teresa Rocchetti, Ighli di Bari, Claudio Mastropaolo, Rossella Labarile, Roberta Ragni, Loreto Gesualdo, Gianluca Maria Farinola, Danilo Vona

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Stefania Roberta CiccoConsiglio Nazionale delle Ricerche, CNR-ICCOM, Via E. Orabona 4, 70126 Bari, Italy.ORCID 0000-0001-7446-7445
Maria Michela GiangregorioInstitute of Nanotechnology, CNR-NANOTEC, Via Orabona 4, 70126 Bari, Italy.
Maria Teresa RocchettiDepartment of Clinical and Experimental Medicine, University of Foggia, Via Pinto 1, 71122 Foggia, Italy.ORCID 0000-0002-2397-6474
Ighli di BariDipartimento di Emergenza e Trapianto di Organi, Nefrologia, Dialisi e Unità Trapianti, Università Degli Studi di Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.
Claudio MastropaoloVisionage SRL, Via Marconi 19, 70011 Alberobello, Italy.
Rossella LabarileDipartimento di Chimica, Università Degli Studi di Bari "Aldo Moro", Via E. Orabona 4, 70126 Bari, Italy.ORCID 0000-0003-0717-3679
Roberta RagniDipartimento di Chimica, Università Degli Studi di Bari "Aldo Moro", Via E. Orabona 4, 70126 Bari, Italy.
Loreto GesualdoDipartimento di Emergenza e Trapianto di Organi, Nefrologia, Dialisi e Unità Trapianti, Università Degli Studi di Bari "Aldo Moro", Piazza G. Cesare 11, 70124 Bari, Italy.ORCID 0000-0002-4861-0911
Gianluca Maria FarinolaDipartimento di Chimica, Università Degli Studi di Bari "Aldo Moro", Via E. Orabona 4, 70126 Bari, Italy.
Danilo VonaDipartimento di Chimica, Università Degli Studi di Bari "Aldo Moro", Via E. Orabona 4, 70126 Bari, Italy.
University of Bari Aldo Moro · ITInstitute for Chemical and Physical Processes · ITInstitute for the Chemistry of OrganoMetallic Compounds · ITIstituto di Nanotecnologia · ITUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polydopamine (PDA) is a synthetic eumelanin polymer mimicking the biopolymer secreted by mussels to attach to surfaces with a high binding strength. It exhibits unique adhesive properties and has recently attracted considerable interest as a multifunctional thin film coating. In this study, we demonstrate that a PDA coating on silica- and polymer-based materials improves the entrapment and retention of uremic toxins produced in specific diseases. The low-cost natural nanotextured fossil diatomaceous earth (DE), an abundant source of mesoporous silica, and polyvinylpyrrolidone-co-Styrene (PVP-co-S), a commercial absorbent comprising polymeric particles, were easily coated with a PDA layer by oxidative polymerization of dopamine at mild basic aqueous conditions. An in-depth chemical-physical investigation of both the resulting PDA-coated materials was performed by SEM, AFM, UV-visible, Raman spectroscopy and spectroscopic ellipsometry. Finally, the obtained hybrid systems were successfully tested for the removal of two uremic toxins (indoxyl sulfate and p-cresyl sulfate) directly from patients' sera.

Indexed as

IndicanPovidoneDiatomaceous EarthHumansIndolesPolymersPolyvinyl ChlorideSilicon DioxideStyrenesSulfatesUremic ToxinsDiatomaceous EarthIndicanIndolespolydopaminePolymersPolyvinyl ChloridePovidoneSilicon DioxideStyrenesSulfatesUremic Toxinsbioremovalchemical functionalizationdiatomaceous earthpolydopaminepolyvinylpyrrolidone-co-styreneuremic toxins

Identifiers

PMID36548761
PMCPMC9781211
OpenAlexW4311970281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.