Evidence map›Paper›PMID 36548672›Full record

ArticleTropical medicine and infectious disease2022

Antiplasmodial Properties of Aqueous and Ethanolic Extracts of Ten Herbal Traditional Recipes Used in Thailand against

Arisara Phuwajaroanpong, Prapaporn Chaniad, Walaiporn Plirat, Sathianpong Phoopha, Abdi Wira Septama, Arnon Chukaew, Chuchard Punsawad

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Arisara PhuwajaroanpongDepartment of Medical Sciences, School of Medicine, Walailak University, Nakhon Si Thammarat 80160, Thailand.
Prapaporn ChaniadDepartment of Medical Sciences, School of Medicine, Walailak University, Nakhon Si Thammarat 80160, Thailand.
Walaiporn PliratDepartment of Medical Sciences, School of Medicine, Walailak University, Nakhon Si Thammarat 80160, Thailand.
Sathianpong PhoophaTraditional Thai Medical Research and Innovation Center, Faculty of Traditional Thai Medicine, Prince of Songkla University, Songkhla 90110, Thailand.ORCID 0000-0003-3690-1575
Abdi Wira SeptamaCenter for Pharmaceutical Ingredient and Traditional Medicine, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor 16915, Indonesia.
Arnon ChukaewChemistry Department, Faculty of Science and Technology, Suratthani Rajabhat University, Surat Tani 84100, Thailand.
Chuchard PunsawadDepartment of Medical Sciences, School of Medicine, Walailak University, Nakhon Si Thammarat 80160, Thailand.ORCID 0000-0003-4826-9474

Funding

Walailak University Graduate Research Fund, Thailand CGS-RF-2022/06
6 · The paper itself

Abstract

This study evaluated the in vitro and in vivo antiplasmodial efficacy and toxicity of aqueous and ethanolic extracts from traditional recipes used in Thailand. The aqueous and ethanolic extracts of ten traditional recipes were tested for in vitro antiplasmodial activity (parasite lactate dehydrogenase assay), cytotoxicity (MTT assay), and hemolysis). Oxidant levels were measured using cell-permeable probe 5-(and-6)-chloromethyl-2',7'-dichlorodihydrofluorescein diacetate fluorescent dye-based assays. The best candidate was chosen for testing in mouse models using 4-day suppressive and acute toxicity assays. An in vitro study showed that ethanolic extracts and three aqueous extracts exhibited antiplasmodial activity, with an IC

Indexed as

antimalarial activityantiplasmodial activitycytotoxicityhemolysisherbal recipeoxidant

Identifiers

PMID36548672
PMCPMC9786625

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.