Evidence map›Paper›PMID 36548572›Full record

ArticleToxics2022

Antibiotic Toxicity Isolated and as Binary Mixture to Freshwater Algae

Fang Chang, Malan Yi, Huiting Li, Jiangnan Wang, Xuefeng Zhao, Xiaoyue Hu, Qianju Qi

Abstract read
In one paragraph

Article in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fang ChangMarine Resources Research Centre, Tianjin Research Institute for Water Transport Engineering, M.O.T., Tianjin 300456, China.
Malan YiMarine Resources Research Centre, Tianjin Research Institute for Water Transport Engineering, M.O.T., Tianjin 300456, China.
Huiting LiMarine Resources Research Centre, Tianjin Research Institute for Water Transport Engineering, M.O.T., Tianjin 300456, China.ORCID 0000-0002-1945-6003
Jiangnan WangMarine Resources Research Centre, Tianjin Research Institute for Water Transport Engineering, M.O.T., Tianjin 300456, China.
Xuefeng ZhaoHanjiang Bureau of Hydrology and Water Resources, Bureau of Hydrology, Changjiang Water Resources Commission, Xiangyang 441000, China.
Xiaoyue HuHanjiang Bureau of Hydrology and Water Resources, Bureau of Hydrology, Changjiang Water Resources Commission, Xiangyang 441000, China.
Qianju QiMarine Resources Research Centre, Tianjin Research Institute for Water Transport Engineering, M.O.T., Tianjin 300456, China.

Funding

The research project of Shanghai Science and Technology Commission; he National Nonprofit Institute Research Grants of TIWTE NO. 19DZ1204303; NO. TKS20220204
6 · The paper itself

Abstract

Antibiotics in aqueous environments can have extremely adverse effects on non-targeted organisms. However, many research projects have only focused on the toxicological evaluation of individual antibiotics in various environments. In the present work, individual and binary mixture toxicity experiments have been conducted with the model organism Raphidocelis subcapitata (R. subcapitata), and a mixture concentration-response curve was established and contrasted with the estimated effects on the basis of both the concentration addition (CA) and the independent action (IA) models. In addition, different risk assessment methods were used and compared to evaluate the environmental risk of binary mixtures. The toxic ranking of the selected antibiotics to R. subcapitata was erythromycin (ERY) > sulfamethoxazole (SMX) > sulfamethazine (SMZ). In general, the conclusion of this study is that the adverse effects of binary mixtures are higher than the individual antibiotics. The CA model and RQSTU are more suitable for toxicity prediction and risk assessment of binary mixtures. This study reveals the potential ecological risks that antibiotics and their mixtures may pose to water ecosystems, thus providing scientific information for environmental quality regulation.

Indexed as

algaeantibioticsCA and IA modelsenvironmental risk assessmentmixture toxicity

Identifiers

PMID36548572
PMCPMC9785756

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.