Evidence map›Paper›PMID 36548549›Full record

ReviewToxics2022

Characterization of the Toxicological Impact of Heavy Metals on Human Health in Conjunction with Modern Analytical Methods.

Dana Claudia Filipoiu, Simona Gabriela Bungau, Laura Endres, Paul Andrei Negru, Alexa Florina Bungau, Bianca Pasca, Andrei-Flavius Radu, Alexandra Georgiana Tarce, Mihaela Alexandra Bogdan, Tapan Behl and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Toxics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  14. Immunogenetic and Environmental Factors in Age-Related Macular Disease.International journal of molecular sciences · 2024
    Review
  15. Article
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  18. The Antioxidant Properties and Protective Capacity ofAntioxidants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Dana Claudia FilipoiuDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410073 Oradea, Romania.
Simona Gabriela BungauDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410073 Oradea, Romania.ORCID 0000-0003-3236-1292
Laura EndresDepartment of Psycho-neurosciences and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.ORCID 0000-0002-3315-2364
Paul Andrei NegruDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410073 Oradea, Romania.
Alexa Florina BungauDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410073 Oradea, Romania.
Bianca PascaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania.
Andrei-Flavius RaduDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410073 Oradea, Romania.
Alexandra Georgiana TarceMedicine Program of Study, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Mihaela Alexandra BogdanDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania.
Tapan BehlDepartment of Pharmacology, School of Health Sciences & Technology (SoHST), University of Petroleum and Energy Studies, Bidholi 248007, India.
Aurelia Cristina NechiforAnalytical Chemistry and Environmental Engineering Department, Polytechnic University of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0001-8891-8948
Syed Shams Ul HassanShanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0000-0001-5188-6540
Delia Mirela TitDoctoral School of Biological and Biomedical Sciences, University of Oradea, 410073 Oradea, Romania.ORCID 0000-0002-0296-6592
University of Oradea · ROShanghai Jiao Tong University · CNUniversity of Bucharest · ROUniversity of Petroleum and Energy Studies · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased environmental pollution, urbanization, and a wide variety of anthropogenic activities have led to the release of toxic pollutants into the environment, including heavy metals (HMs). It has been found that increasing concentrations of HMs lead to toxicity, mineral imbalances, and serious diseases, which are occurring more and more frequently. Therefore, testing has become imperative to detect these deficiencies in a timely manner. The detection of traces of HMs, especially toxic ones, in human tissues, various biological fluids, or hair is a complex, high-precision analysis that enables early diagnosis, addressing people under constant stress or exposed to a toxic environment; the test also targets people who have died in suspicious circumstances. Tissue mineral analysis (TMA) determines the concentration of toxic minerals/metals at the intracellular level and can therefore determine correlations between measured concentrations and imbalances in the body. Framing the already-published information on the topic, this review aimed to explore the toxicity of HMs to human health, the harmful effects of their accumulation, the advantages vs. the disadvantages of choosing different biological fluids/tissues/organs necessary for the quantitative measurement of HM in the human body, as well as the choice of the optimal method, correlated with the purpose of the analysis.

Indexed as

bibliometric analysisenvironmental pollutionheavy metalshuman healthmineralogramtissue mineral analysistoxic effect

Identifiers

PMID36548549
PMCPMC9785207
OpenAlexW4309852273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.