Evidence map›Paper›PMID 36548400›Full record

ArticleAnalytical chemistry2023

A High-Throughput Amenable Dual Luciferase System for Measuring

David Smith, Matteo Lunghi, Einar B Olafsson, Olivia Hatton, Manlio Di Cristina, Vern B Carruthers

Open access · bronzeAbstract read
In one paragraph

Article in Analytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. bioRxiv : the preprint server for biology · 2026
    Article
  2. Bioluminescence-basedFrontiers in cellular and infection microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

David SmithUniversity of Michigan Medical School, Ann Arbor 734 763 2081, United States.ORCID 0000-0002-5158-0522
Matteo LunghiUniversità degli Studi di Perugia, Perugia 06123, Italy.
Einar B OlafssonUniversity of Michigan Medical School, Ann Arbor 734 763 2081, United States.
Olivia HattonUniversity of Michigan Medical School, Ann Arbor 734 763 2081, United States.
Manlio Di CristinaUniversità degli Studi di Perugia, Perugia 06123, Italy.
Vern B CarruthersUniversity of Michigan Medical School, Ann Arbor 734 763 2081, United States.
University of Michigan · USUniversity of Perugia · ITUppsala University · SE

Funding

Parasite autophagy as a key survival mechanism for the AIDS-associated pathogen Toxoplasma gondiiR01AI120607 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARRUTHERS, VERNON BRUCE · 2016 to 2025
$4.0M
Rational design of CNS-permeable cathepsin L inhibitors for treatment of chronic toxoplasmosisR33AI127492 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARRUTHERS, VERNON BRUCE, WHITE, ANDREW DAVID · 2019 to 2021
$1.3M
NIAID NIH HHS R01 AI120607NIAID NIH HHS R33 AI127492
6 · The paper itself

Abstract

It is estimated that more than 2 billion people are chronically infected with the intracellular protozoan parasite

Indexed as

ToxoplasmaAtovaquoneHumansLuciferasesLuciferases, FireflyAtovaquoneLuciferasesLuciferases, Firefly

Identifiers

PMID36548400
PMCPMC9850410
OpenAlexW4312113428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.