Evidence map›Paper›PMID 36547921›Full record

ReviewMarine drugs2022

Marine Polyphenol Phlorotannins as a Natural Sleep Aid for Treatment of Insomnia: A Review of Sedative-Hypnotic Effects and Mechanism of Action.

Seonghui Kim, Duhyeon Kim, Min Young Um, Minseok Yoon, Jae-Suk Choi, Yung Hyun Choi, Suengmok Cho

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Effects ofJournal of microbiology and biotechnology · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Seonghui KimDepartment of Food Science and Technology, Institute of Food Science, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0003-4627-3664
Duhyeon KimDepartment of Food Science and Technology, Institute of Food Science, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0002-6269-1551
Min Young UmResearch Division of Food Functionality, Korea Food Research Institute, Wanju 55365, Republic of Korea.ORCID 0000-0002-8448-8837
Minseok YoonResearch Division of Food Functionality, Korea Food Research Institute, Wanju 55365, Republic of Korea.
Jae-Suk ChoiDepartment of Seafood Science and Technology, The Institute of Marine Industry, Gyeongsang National University, 38 Cheondaegukchi-gil, Tongyeong-si 53064, Republic of Korea.ORCID 0000-0002-8151-6054
Yung Hyun ChoiDepartment of Biochemistry, College of Korean Medicine, Dong-Eui University, Busan 47227, Republic of Korea.ORCID 0000-0002-1454-3124
Suengmok ChoDepartment of Food Science and Technology, Institute of Food Science, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0001-5951-5832
Pukyong National University · KRKorea Food Research Institute · KRDong-Eui University · KRGyeongsang National University · KR

Funding

This research was supported by the Korea Institute of Marine Science & Technology Promotion (KIMST), funded by the Ministry of Oceans and Fisheries 20220488, 20220128
6 · The paper itself

Abstract

Insomnia is a common sleep disorder. Natural sleep aids are gaining worldwide popularity as alternatives to prescription drugs for improving sleep. Recently, numerous studies have investigated the sedative-hypnotic effects of the polyphenols of terrestrial plants. The hypnotic effects of marine polyphenols have also been studied in recent years. Phlorotannins are marine polyphenols that are found only in brown algae. Phlorotannins exert sedative-hypnotic effects via the gamma-aminobutyric acid type A-benzodiazepine receptor. In addition, the brown seaweed

Indexed as

PhaeophyceaeSeaweedSleep Initiation and Maintenance DisordersAnimalsHumansHypnotics and SedativesPolyphenolsSleepHypnotics and SedativesPolyphenolsGABAergic mechanisminsomniamarine polyphenolphlorotanninsleep

Identifiers

PMID36547921
PMCPMC9780786
OpenAlexW4311154111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.