Evidence map›Paper›PMID 36547919›Full record

ReviewMarine drugs2022

Biological Properties and Health-Promoting Functions of Laminarin: A Comprehensive Review of Preclinical and Clinical Studies.

Shanmugapriya Karuppusamy, Gaurav Rajauria, Stephen Fitzpatrick, Henry Lyons, Helena McMahon, James Curtin, Brijesh K Tiwari, Colm O'Donnell

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
19.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 102 citations in OpenAlex.

  1. Article
  2. Review
  3. Biomimetic materials for medical applications.Chinese medical journal · 2026
    Review
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shanmugapriya KaruppusamySchool of Biosystems and Food Engineering, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-9923-7432
Gaurav RajauriaDepartment of Biological and Pharmaceutical Sciences, Munster Technological University, Clash, V92 CX88 Tralee, Ireland.ORCID 0000-0001-5276-6962
Stephen FitzpatrickNutramara Ltd., Beechgrove House Strand Street, V92 FH0K Tralee, Ireland.ORCID 0000-0003-3929-4109
Henry LyonsNutramara Ltd., Beechgrove House Strand Street, V92 FH0K Tralee, Ireland.ORCID 0000-0001-7482-4414
Helena McMahonCircular Bioeconomy Research Group, Shannon Applied Biotechnology Centre, Munster Technological University, V92 CX88 Tralee, Ireland.ORCID 0000-0002-4416-0300
James CurtinSchool of Food Science and Environmental Health, College of Sciences and Health, Technological University Dublin, D01 K822 Dublin, Ireland.ORCID 0000-0002-9320-9254
Brijesh K TiwariTeagasc Food Research Centre, Department of Food Chemistry and Technology, Ashtown, D15 KN3K Dublin, Ireland.ORCID 0000-0002-4834-6831
Colm O'DonnellSchool of Biosystems and Food Engineering, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.ORCID 0000-0002-8004-450X
Shannon Applied Biotechnology Centre · IEUniversity College Dublin · IETeagasc - The Irish Agriculture and Food Development Authority · IETechnological University Dublin · IE

Funding

Enterprise Ireland MSCA20210184
6 · The paper itself

Abstract

Marine algal species comprise of a large portion of polysaccharides which have shown multifunctional properties and health benefits for treating and preventing human diseases. Laminarin, or β-glucan, a storage polysaccharide from brown algae, has been reported to have potential pharmacological properties such as antioxidant, anti-tumor, anti-coagulant, anticancer, immunomodulatory, anti-obesity, anti-diabetic, anti-inflammatory, wound healing, and neuroprotective potential. It has been widely investigated as a functional material in biomedical applications as it is biodegradable, biocompatible, and is low toxic substances. The reported preclinical and clinical studies demonstrate the potential of laminarin as natural alternative agents in biomedical and industrial applications such as nutraceuticals, pharmaceuticals, functional food, drug development/delivery, and cosmeceuticals. This review summarizes the biological activities of laminarin, including mechanisms of action, impacts on human health, and reported health benefits. Additionally, this review also provides an overview of recent advances and identifies gaps and opportunities for further research in this field. It further emphasizes the molecular characteristics and biological activities of laminarin in both preclinical and clinical settings for the prevention of the diseases and as potential therapeutic interventions.

Indexed as

GlucansPhaeophyceaeHumansPharmaceutical PreparationsPolysaccharidesGlucanslaminaranPharmaceutical PreparationsPolysaccharidesalgal polysaccharidebioactive compoundsbiological activitybiomedical applicationclinicalhuman healthlaminarinpreclinical

Identifiers

PMID36547919
PMCPMC9780867
OpenAlexW4311154098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.