Evidence map›Paper›PMID 36547914›Full record

ArticleMarine drugs2022

Enhancing Bioproducts in Seaweeds via Sustainable Aquaculture: Antioxidant and Sun-Protection Compounds.

Doron Yehoshua Ashkenazi, Félix L Figueroa, Nathalie Korbee, Marta García-Sánchez, Julia Vega, Shoshana Ben-Valid, Guy Paz, Eitan Salomon, Álvaro Israel, Avigdor Abelson

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Doron Yehoshua AshkenaziSchool of Zoology, Tel Aviv University, Ramat Aviv, Tel Aviv-Yafo 69978, Israel.ORCID 0000-0002-2841-6900
Félix L FigueroaAndalusian Institute for Biotechnology and Blue Development (IBYDA), Experimental Center Grice Hutchinson, Malaga University, Lomas de San Julián, 2, 29004 Málaga, Spain.ORCID 0000-0003-3580-4693
Nathalie KorbeeAndalusian Institute for Biotechnology and Blue Development (IBYDA), Experimental Center Grice Hutchinson, Malaga University, Lomas de San Julián, 2, 29004 Málaga, Spain.ORCID 0000-0002-9780-4915
Marta García-SánchezAndalusian Institute for Biotechnology and Blue Development (IBYDA), Experimental Center Grice Hutchinson, Malaga University, Lomas de San Julián, 2, 29004 Málaga, Spain.
Julia VegaAndalusian Institute for Biotechnology and Blue Development (IBYDA), Experimental Center Grice Hutchinson, Malaga University, Lomas de San Julián, 2, 29004 Málaga, Spain.ORCID 0000-0002-7473-5961
Shoshana Ben-ValidSchool of Zoology, Tel Aviv University, Ramat Aviv, Tel Aviv-Yafo 69978, Israel.
Guy PazIsrael Oceanographic & Limnological Research Ltd. (PBC), Tel Shikmona, P.O. Box 9753, Haifa 3109701, Israel.
Eitan SalomonIsrael Oceanographic and Limnological Research, National Center for Mariculture, P.O. Box 1212, Eilat 8811201, Israel.ORCID 0000-0002-6245-3131
Álvaro IsraelIsrael Oceanographic & Limnological Research Ltd. (PBC), Tel Shikmona, P.O. Box 9753, Haifa 3109701, Israel.
Avigdor AbelsonSchool of Zoology, Tel Aviv University, Ramat Aviv, Tel Aviv-Yafo 69978, Israel.
Universidad de Málaga · ESIsrael Oceanographic and Limnological Research · ILTel Aviv University · IL

Funding

Ministry of Health, Israel 3-16052
6 · The paper itself

Abstract

Marine macroalgae are considered an untapped source of healthy natural metabolites and their market demand is rapidly increasing. Intertidal macroalgae present chemical defense mechanisms that enable them to thrive under changing environmental conditions. These intracellular chemicals include compounds that can be used for human benefit. The aim of this study was to test cultivation protocols that direct seaweed metabolic responses to enhance the production of target antioxidant and photoprotective biomaterials. We present an original integrated multi-trophic aquaculture (IMTA) design, based on a two-phase cultivation plan, in which three seaweed species were initially fed by fish effluents, and subsequently exposed to various abiotic stresses, namely, high irradiance, nutrient starvation, and high salinity. The combined effect of the IMTA's high nutrient concentrations and/or followed by the abiotic stressors enhanced the seaweeds' content of mycosporine-like amino acids (MAAs) by 2.3-fold, phenolic compounds by 1.4-fold, and their antioxidant capacity by 1.8-fold. The Sun Protection Factor (SPF) rose by 2.7-fold, and the chlorophyll and phycobiliprotein synthesis was stimulated dramatically by an order of magnitude. Our integrated cultivation system design offers a sustainable approach, with the potential to be adopted by emerging industries for food and health applications.

Indexed as

AntioxidantsSeaweedAmino AcidsAnimalsAquacultureFishesHumansAmino AcidsAntioxidantsantioxidantsbioproductsGracilariaintegrated aquaculturemycosporine-like amino acidsphenolic compoundspigmentsseaweedssun protection factorUlva

Identifiers

PMID36547914
PMCPMC9787370
OpenAlexW4311856781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.