Evidence map›Paper›PMID 36547900›Full record

ArticleMarine drugs2022

Insights into the Influence of Signal Peptide on the Enzymatic Properties of Alginate Lyase AlyI1 with Removal Effect on

Ming-Jing Zhang, Shuai-Ting Yun, Xiao-Chen Wang, Li-Yang Peng, Chuan Dou, Yan-Xia Zhou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ming-Jing ZhangMarine College, Shandong University, Weihai 264209, China.
Shuai-Ting YunMarine College, Shandong University, Weihai 264209, China.
Xiao-Chen WangMarine College, Shandong University, Weihai 264209, China.
Li-Yang PengMarine College, Shandong University, Weihai 264209, China.
Chuan DouShangdong Kelun Pharmaceutical Co., Ltd., Bingzhou 256600, China.
Yan-Xia ZhouMarine College, Shandong University, Weihai 264209, China.ORCID 0000-0003-0393-8136
Shandong University · CNKelun Group (China) · CN

Funding

China Postdoctoral Science Foundation 2017M62218National Natural Science Foundation of China 31700116Natural Science Foundation of Shandong Province ZR2017MC019The Key Science and Technology Program of Weihai 1070413421511
6 · The paper itself

Abstract

Most reports on signal peptides focus on their ability to affect the normal folding of proteins, thereby affecting their secreted expression, while few studies on its effects on enzymatic properties were published. Therefore, biochemical characterization and comparison of alginate lyase rALYI1/rALYI1-1 (rALYI1: without signal peptides; rALYI1-1:with signal peptides) were conducted in our study, and the results showed that the signal peptide affected the biochemical properties, especially in temperature and pH. rALYI1 (32.15 kDa) belonging to polysaccharide lyase family 7 was cloned from sea-cucumber-gut bacterium

Indexed as

BiofilmsFlavobacteriaceaePolysaccharide-LyasesProtein Sorting SignalsPseudomonas aeruginosaAlginatesHydrogen-Ion ConcentrationSubstrate SpecificityAlginatespoly(beta-D-mannuronate) lyasePolysaccharide-LyasesProtein Sorting Signalsalginate lyasePseudomonas aeruginosa biofilmsalt activatedsignal peptide

Identifiers

PMID36547900
PMCPMC9787728
OpenAlexW4310383307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.