Evidence map›Paper›PMID 36547892›Full record

ArticleMarine drugs2022

Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota.

Noémie De San Nicolas, Aromal Asokan, Rafael D Rosa, Sébastien N Voisin, Marie-Agnès Travers, Gustavo Rocha, Luc Dantan, Yann Dorant, Guillaume Mitta, Bruno Petton and 11 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. When the microbiome shapes the host: immune evolution implications for infectious disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  3. Cross-talk and mutual shaping between the immune system and the microbiota during an oyster's life.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 3 countries.

Noémie De San NicolasIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.ORCID 0000-0001-5114-8732
Aromal AsokanCentre de Biophysique Moléculaire UPR4301 CNRS, 45071 Orléans, France.
Rafael D RosaLaboratory of Immunology Applied to Aquaculture, Department of Cell Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.ORCID 0000-0002-4076-3163
Sébastien N VoisinPlateforme BioPark d'Archamps, Archparc, 74160 Archamps, France.ORCID 0000-0001-5897-333X
Marie-Agnès TraversIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.
Gustavo RochaLaboratory of Immunology Applied to Aquaculture, Department of Cell Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil.
Luc DantanIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.ORCID 0000-0001-6894-5762
Yann DorantIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.
Guillaume MittaIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.
Bruno PettonIfremer, CNRS, IRD, Ifremer, LEMAR UMR 6539, Université de Bretagne Occidentale, 29840 Argenton-en-Landunvez, France.
Guillaume M CharrièreIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.ORCID 0000-0002-4796-1488
Jean-Michel EscoubasIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.ORCID 0000-0002-6138-1148
Viviane BouloIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.
Juliette PouzadouxIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.
Hervé MeudalCentre de Biophysique Moléculaire UPR4301 CNRS, 45071 Orléans, France.ORCID 0000-0002-9642-3643
Karine LothCentre de Biophysique Moléculaire UPR4301 CNRS, 45071 Orléans, France.
Vincent AucagneCentre de Biophysique Moléculaire UPR4301 CNRS, 45071 Orléans, France.ORCID 0000-0002-2647-0188
Agnès F DelmasCentre de Biophysique Moléculaire UPR4301 CNRS, 45071 Orléans, France.
Philippe BuletPlateforme BioPark d'Archamps, Archparc, 74160 Archamps, France.ORCID 0000-0001-9016-265X
Caroline MontagnaniIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.ORCID 0000-0002-0861-7967
Delphine Destoumieux-GarzónIHPE, University Montpellier, CNRS, Ifremer, University Perpignan Via Domitia, 34090 Montpellier, France.ORCID 0000-0002-8793-9138
Centre National de la Recherche Scientifique · FRUniversidade Federal de Santa Catarina · BRUniversité d'Orléans · FR

Funding

Agence Nationale de la Recherche ANR-19-CE18-0025Agence Nationale de la Recherche ANR-19-CE20-0004labex TULIP ANR-10-LABX-41University of Montpellier KIM18SEA-FRV10-DESTOURN
6 · The paper itself

Abstract

Big defensins are two-domain antimicrobial peptides (AMPs) that have highly diversified in mollusks.

Indexed as

CrassostreaDefensinsAnimalsAnti-Bacterial AgentsBacteriaAnti-Bacterial AgentsDefensinsantibacterial peptidebeta defensindiversityevolutioninvertebratemicrobiomemollusk

Identifiers

PMID36547892
PMCPMC9786018
OpenAlexW4310197294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.