Evidence map›Paper›PMID 36547779›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2023

Clinimetrics of the cognitive section of the Italian ALS Cognitive Behavioral Screen (ALS-CBS™).

Edoardo Nicolò Aiello, Lucia Catherine Greco, Antonino La Tona, Federica Solca, Silvia Torre, Laura Carelli, Debora Pain, Alice Radici, Andrea Lizio, Jacopo Casiraghi and 13 more

Abstract read
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Ecological validity of performance-based cognitive screeners in amyotrophic lateral sclerosis: preliminary evidence.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 9 institutions in 2 countries.

Edoardo Nicolò Aiello *Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Piazzale Brescia 20, 20149, Milan, Italy.
Lucia Catherine Greco *Neuromuscular Omnicentre (NEMO), Fondazione Serena Onlus, Milan, Italy.
Antonino La TonaDepartment of Human and Social Sciences, University of Bergamo, Bergamo, Italy.
Federica SolcaDepartment of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Piazzale Brescia 20, 20149, Milan, Italy.
Silvia TorreDepartment of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Piazzale Brescia 20, 20149, Milan, Italy.
Laura CarelliDepartment of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Piazzale Brescia 20, 20149, Milan, Italy.
Debora PainIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of Milan Institute, Milan, Italy.
Alice RadiciIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of Milan Institute, Milan, Italy.
Andrea LizioNeuromuscular Omnicentre (NEMO), Fondazione Serena Onlus, Milan, Italy.
Jacopo CasiraghiNeuromuscular Omnicentre (NEMO), Fondazione Serena Onlus, Milan, Italy.
Federica CerriNeuromuscular Omnicentre (NEMO), Fondazione Serena Onlus, Milan, Italy.
Agostino BrugneraDepartment of Human and Social Sciences, University of Bergamo, Bergamo, Italy.
Angelo CompareDepartment of Human and Social Sciences, University of Bergamo, Bergamo, Italy.
Susan WoolleySyneos Health, Morrisville, NC, USA.
Jennifer MurphyBiogen, Cambridge, MA, USA.
Lucio TremolizzoSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Ildebrando AppollonioSchool of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Federico VerdeDepartment of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Piazzale Brescia 20, 20149, Milan, Italy.
Vincenzo SilaniDepartment of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Piazzale Brescia 20, 20149, Milan, Italy.
Nicola TicozziDepartment of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Piazzale Brescia 20, 20149, Milan, Italy.
Christian LunettaIstituti Clinici Scientifici Maugeri IRCCS, Neurorehabilitation Department of Milan Institute, Milan, Italy.
Valeria Ada Sansone *PhD Program in Neuroscience, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Barbara Poletti *Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Piazzale Brescia 20, 20149, Milan, Italy. b.poletti@auxologico.it.ORCID http://orcid.org/0000-0003-4398-2051
IRCCS Istituto Auxologico Italiano · ITUniversity of Milan · ITCentro Clinico Nemo · ITIstituti Clinici Scientifici Maugeri · ITUniversity of Bergamo · ITUniversity of Milano-Bicocca · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITBiogen (United States) · USSyneos Health (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study aimed at (1) providing further validity and reliability evidence for the Italian version of the cognitive section of the ALS Cognitive Behavioral Screen (ALS-CBS™) and (2) testing its diagnostics within an Italian ALS cohort, as well as at (3) exploring its capability to discriminate patients from healthy controls (HCs).

methodsN = 293 non-demented ALS patients were administered the cognitive sections of the ALS-CBS™ and Edinburgh Cognitive and Behavioural ALS Screen (ECAS). N = 96 HCs demographically matched with N = 96 patients were also administered the cognitive section of the ALS-CBS™. In patients, factorial and construct validity, internal reliability, and diagnostics against a defective score on the cognitive section of the ECAS were tested. Case-control discrimination was assessed via a logistic regression.

resultsALS-CBS™ cognitive subscales were underpinned by a simple, unidimensional structure, internally reliable (McDonald's ω = 0.74), and mostly related with ECAS executive and fluency scores (r DISCUSSION: The cognitive section of the Italian ALS-CBS™ is a valid, reliable, and diagnostically sound ALS-specific screener for detecting frontotemporal, executive-/attentive-based cognitive inefficiency in non-demented ALS patients, being also able to discriminate them from normotypical individuals.

Indexed as

Amyotrophic Lateral SclerosisCognition DisordersCognitive DysfunctionCognitionHumansItalyNeuropsychological TestsReproducibility of ResultsALS Cognitive Behavioral ScreenAmyotrophic lateral sclerosisClinimetricsCognitive screeningFrontotemporal degenerationNeuropsychology

Identifiers

PMID36547779
OpenAlexW4312095760

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.