Evidence map›Paper›PMID 36547601›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

Effect of Flagellin Pre-Exposure on the Inflammatory and Antifungal Response of Bronchial Epithelial Cells to Fungal Pathogens.

Jeanne Bigot, Manon Ruffin, Juliette Guitard, Sandra Vellaissamy, Sophie Thorez, Harriet Corvol, Loïc Guillot, Viviane Balloy, Christophe Hennequin

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jeanne BigotCentre de Recherche Saint-Antoine (CRSA), Inserm, AP-HP, Hôpital Saint-Antoine, Service de Parasitologie-Mycologie, Sorbonne Université, F-75012 Paris, France.ORCID 0000-0002-4495-8937
Manon RuffinCentre de Recherche Saint-Antoine (CRSA), Inserm, Sorbonne Université, F-75012 Paris, France.
Juliette GuitardCentre de Recherche Saint-Antoine (CRSA), Inserm, AP-HP, Hôpital Saint-Antoine, Service de Parasitologie-Mycologie, Sorbonne Université, F-75012 Paris, France.ORCID 0000-0002-9782-3577
Sandra VellaissamyAP-HP, Hôpital Saint-Antoine, Service de Parasitologie-Mycologie, F-75012 Paris, France.
Sophie ThorezAP-HP, Hôpital Saint-Antoine, Service de Parasitologie-Mycologie, F-75012 Paris, France.
Harriet CorvolCentre de Recherche Saint-Antoine (CRSA), Inserm, AP-HP, Hôpital Trousseau, Service de Pneumologie Pédiatrique, Sorbonne Université, F-75012 Paris, France.ORCID 0000-0002-7026-7523
Loïc GuillotCentre de Recherche Saint-Antoine (CRSA), Inserm, Sorbonne Université, F-75012 Paris, France.ORCID 0000-0001-6853-7945
Viviane BalloyCentre de Recherche Saint-Antoine (CRSA), Inserm, Sorbonne Université, F-75012 Paris, France.
Christophe HennequinCentre de Recherche Saint-Antoine (CRSA), Inserm, AP-HP, Hôpital Saint-Antoine, Service de Parasitologie-Mycologie, Sorbonne Université, F-75012 Paris, France.ORCID 0000-0002-4528-927X
Inserm · FRSorbonne Université · FR

Funding

Air Liquide (France) R20087DD RAK20016DDAVaincre la Mucoviscidose RF20200502697
6 · The paper itself

Abstract

Bronchial epithelial cells (BEC) play a crucial role in innate immunity against inhaled fungi. Indeed, in response to microorganisms, BEC synthesize proinflammatory cytokines involved in the recruitment of neutrophils. We have recently shown that BEC exert antifungal activity against

Indexed as

bronchial epithelial cellschronic pulmonary diseasesfungal infectioninnate immune memory

Identifiers

PMID36547601
PMCPMC9782670
OpenAlexW4311051516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.