Evidence map›Paper›PMID 36547592›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

Multiple F-Box Proteins Collectively Regulate Cell Development and Pathogenesis in the Human Pathogen

Chengjun Cao, Yina Wang, Samantha L Avina, John Walter, Chaoyang Xue

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chengjun CaoPublic Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ 07103, USA.ORCID 0000-0001-6814-6338
Yina WangPublic Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ 07103, USA.ORCID 0000-0003-1909-728X
Samantha L AvinaPublic Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ 07103, USA.ORCID 0000-0002-3918-7971
John WalterPublic Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ 07103, USA.
Chaoyang XuePublic Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ 07103, USA.ORCID 0000-0001-8196-1468
Rutgers, The State University of New Jersey · US

Funding

Rapid production of SARS-CoV-2 molecular clones using CRISPR-based yeast recombineeringR01AI100272 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MADHANI, HITEN D · 2012 to 2025
$11.3M
Mechanisms of vaccine protection against AIDS-associated Cryptococcus infectionR01AI141368 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Amariliz Rivera, Chaoyang Xue · 2019 to 2026
$5.4M
The role of inositol in Cryptococcus biology and pathogenesisR01AI123315 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Chaoyang Xue · 2017 to 2026
$5.0M
Rutgers Optimizes Innovation (ROI) ProgramU01HL150852 · NHLBI · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI LIBUTTI, STEVEN K., PANETTIERI, REYNOLD ALEXANDER · 2019 to 2022
$4.4M
NHLBI NIH HHS U01 HL150852NIAID NIH HHS R01 AI100272NIAID NIH HHS R01 AI123315NIAID NIH HHS R01 AI141368NIH HHS R01AI123315NIH HHS R01AI141368NIH HHS R01AI141368-03S1NIH HHS U01HL150852
6 · The paper itself

Abstract

The ubiquitin-proteasome system (UPS) mediates intracellular proteins degradation that influences various cellular functions in eukaryotic cells. The UPS is also involved in the development and virulence of pathogenic fungi. F-box proteins, which are part of the SCF (Skp1-Cullin-F-box protein) ligase, are a key component of UPS and are essential for the recognition of specific substrates. In this study, we identified 20 F-box proteins in

Indexed as

Cryptococcus neoformansE3 ligaseF-box proteinfungal pathogenesisstress response

Identifiers

PMID36547592
PMCPMC9781138
OpenAlexW4310548551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.