Evidence map›Paper›PMID 36547558›Full record

ArticleJournal of functional biomaterials2022

Degradable Pure Magnesium Used as a Barrier Film for Oral Bone Regeneration.

Xianfeng Shan, Yu Xu, Sharafadeen Kunle Kolawole, Ling Wen, Zhenwei Qi, Weiwei Xu, Junxiu Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xianfeng ShanDepartment of Stomatology, The Affiliated Xinhua Hospital of Dalian University, Dalian 116000, China.
Yu XuKey Laboratory of Materials Surface Science and Technology of Jiangsu Province, Changzhou University, Changzhou 213164, China.
Sharafadeen Kunle KolawoleMechanical Engineering Department, School of Engineering and Technology, Federal Polytechnic, Offa P.M.B 420, Nigeria.ORCID 0000-0002-2193-2515
Ling WenDepartment of Stomatology, The Affiliated Xinhua Hospital of Dalian University, Dalian 116000, China.
Zhenwei QiDepartment of Stomatology, The Affiliated Xinhua Hospital of Dalian University, Dalian 116000, China.
Weiwei XuDepartment of Stomatology, The Affiliated Xinhua Hospital of Dalian University, Dalian 116000, China.
Junxiu ChenKey Laboratory of Materials Surface Science and Technology of Jiangsu Province, Changzhou University, Changzhou 213164, China.
Dalian University · CNChangzhou University · CNThe Federal Polytechnic, Ado-Ekiti · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The barrier membrane plays an extremely critical role in guided bone regeneration (GBR), which determines the success or failure of GBR technology. In order to obtain barrier membranes with high mechanical strength and degradability, some researchers have focused on degradable magnesium alloys. However, the degradation rate of pure Mg-based materials in body fluids is rather fast, thus posing an urgent problem to be solved in oral clinics. In this study, a novel micro-arc oxidation (MAO) surface-treated pure Mg membrane was prepared. Electrochemical tests, immersion experiments and in vivo experiments were carried out to investigate its potential use as a barrier membrane. The experimental results showed that the corrosion resistance of a pure Mg membrane treated by MAO is better than that of the uncoated pure Mg. The results of cell experiments showed no obvious cytotoxicity, which suggests the enhanced differentiation of osteoblasts. At the same time, the MAO-Mg membrane showed better biological activity than the pure Ti membrane in the early stage of implantation, exhibiting relatively good bone regeneration ability. Consequently, the MAO membrane has been proven to possess good application prospects for guided bone regeneration.

Indexed as

bone regenerationcytotoxicitydegradationMAOpure Mg membrane

Identifiers

PMID36547558
PMCPMC9781112
OpenAlexW4312196504

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.