ArticleJournal of functional biomaterials2022
Corrosion Behavior and Biocompatibility of Hot-Extruded Mg-Zn-Ga-(Y) Biodegradable Alloys.
Article in Journal of functional biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Correlative Raman Spectroscopy-SEM Investigations of Sintered Magnesium-Calcium Alloys for Biomedical Applications.Materials (Basel, Switzerland) · 2025Article
- Investigation of Mechanical and Corrosion Properties of New Mg-Zn-Ga Amorphous Alloys for Biomedical Applications.Journal of functional biomaterials · 2024Article
- A Superior Corrosion Protection of Mg Alloy via Smart Nontoxic Hybrid Inhibitor-Containing Coatings.Molecules (Basel, Switzerland) · 2023Article
- An In Vivo Rat Study of Bioresorbable Mg-2Zn-2Ga Alloy Implants.Bioengineering (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Fixation screws and other temporary magnesium alloy fixation devices are used in orthopedic practice because of their biodegradability, biocompatibility and acceptable biodegradation rates. The substitution of dissolving implant by tissues during the healing process is one of the main requirements for biodegradable implants. Previously, clinical tests showed the effectiveness of Ga ions on bone tissue regeneration. This work is the first systematic study on the corrosion rate and biocompatibility of Mg-Zn-Ga-(Y) alloys prepared by hot extrusion, where Ga is an additional major alloying element, efficient as a bone-resorption inhibitor. Most investigated alloys have a low corrosion rate in Hanks' solution close to ~0.2 mm/year. No cytotoxic effects of Mg-2Zn-2Ga (wt.%) alloy on MG63 cells were observed. Thus, considering the high corrosion resistance and good biocompatibility, the Mg-2Zn-2Ga alloy is possible for applications in osteosynthesis implants with improved bone tissue regeneration ability.
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Registered trials
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