Evidence map›Paper›PMID 36547494›Full record

ArticleJournal of imaging2022

3D Ultrasound versus Computed Tomography for Tumor Volume Measurement Compared to Gross Pathology-A Pilot Study on an Animal Model.

Fatemeh Makouei, Caroline Ewertsen, Tina Klitmøller Agander, Mikkel Vestergaard Olesen, Bente Pakkenberg, Tobias Todsen

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Journal of imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05740774 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Feasibility of 3D Ultrasound in the Assessment of Resection Margins During Surgery for Squamous Cell Carcinoma of the Tongue: a Comparison With Histopathology

TypeinterventionalSponsorRigshospitalet, DenmarkRan2023 to 2023Enrolled7ConditionsTongue Cancer, Squamous Cell Carcinoma, Head and Neck CancerArms3D ultrasound
NCT05843032 naunknown statusnot on this mapstarted 2023, after this paper: background citation

3D Ultrasound in the Assessment of Resection Margins During Surgery for Squamous Cell Carcinoma of the Tongue: a Comparison With Clinical Evaluation, MRI, and Histopathology

TypeinterventionalSponsorRigshospitalet, DenmarkRan2023 to 2024Enrolled27ConditionsSquamous Cell Carcinoma, Tongue SCC, Head and Neck CancerArms3D ultrasound, MRI, resected specimen examination by surgeon
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Fatemeh MakoueiDepartment of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.ORCID 0000-0002-6443-7362
Caroline EwertsenDepartment of Radiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.
Tina Klitmøller AganderInstitute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Mikkel Vestergaard OlesenCentre for Neuroscience and Stereology, Department of Neurology, Bispebjerg-Frederiksberg Hospital, DK-2400 Copenhagen, Denmark.
Bente PakkenbergInstitute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Tobias TodsenDepartment of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark.
University of Copenhagen · DKCopenhagen University Hospital · DKFrederiksberg Hospital · DK

Funding

Novo Nordisk Foundation NNF20OC0059290
6 · The paper itself

Abstract

The margin of the removed tumor in cancer surgery has an important influence on survival. Adjuvant treatments, prognostic complications, and financial costs are required when the pathologist observes a close/positive surgical margin. Ex vivo imaging of resected cancer tissue has been suggested for margin assessment, but traditional cross-sectional imaging is not optimal in a surgical setting. Instead, three-dimensional (3D) ultrasound is a portable, high-resolution, and low-cost method to use in the operation room. In this study, we aimed to investigate the accuracy of 3D ultrasound versus computed tomography (CT) to measure the tumor volume in an animal model compared to gross pathology assessment. The specimen was formalin fixated before systematic slicing. A slice-by-slice area measurement was performed to compare the accuracy of the 3D ultrasound and CT techniques. The tumor volume measured by pathological assessment was 980.2 mm

Indexed as

3D ultrasound imaginganimal modelcomputed tomographyex vivo volume analysistumor volume

Identifiers

PMID36547494
PMCPMC9781169
OpenAlexW4312141012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.